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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating activities | |||||
| Net loss | |||||
| Reconciliation of net loss to net cash provided by operating activities: | |||||
| Stock-based compensation | |||||
| Depreciation and amortization | |||||
| Inventory reserves and firm commitment losses | |||||
| Amortization of debt discount and offering costs | |||||
| Change in fair value of derivative liability | |||||
| Change in fair value of contingent liabilities associated with acquisition | |||||
| Loss from termination of revenue interest purchase agreement | |||||
| Costs recognized on sale of acquired inventory | |||||
| Non-cash interest expense related to the revenue interest liability | |||||
| Deferred income taxes associated with an acquisition | |||||
| Gain on sale of priority review voucher, net | |||||
| Unrealized foreign exchange (gain) loss | |||||
| Non-cash lease expense | |||||
| Net accretion of discounts on investments | |||||
| Other | |||||
| Change in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Prepaid and other current assets | |||||
| Inventory | |||||
| Other assets | |||||
| Accounts payable, accrued expenses and other liabilities | |||||
| Operating lease liabilities | |||||
| Net cash provided by (used in) operating activities | |||||
| Investing activities | |||||
| Purchase of investments | |||||
| Proceeds from maturities of investments | |||||
| Proceeds from paydown of investments | |||||
| Purchase of property and equipment | |||||
| Cash paid for acquisition | |||||
| Payments made for additions to intangible assets | |||||
| Proceeds from sale of priority review voucher, net | |||||
| Net cash used in investing activities | |||||
| Financing activities | |||||
| Proceeds from issuance of common stock in private placement, net of issuance costs | |||||
| Proceeds from issuance of common stock in at-the-market offerings, net of issuance costs | |||||
| Proceeds from issuance of common stock in public offerings, net of issuance costs | |||||
| Proceeds from issuance of convertible notes, net | |||||
| Proceeds from issuance of common stock pursuant to equity plans | |||||
| Payments of deferred offering costs | |||||
| Payments on revenue interest liability | |||||
| Proceeds from revenue interest liability, net of issuance costs | |||||
| Net cash provided by financing activities | |||||
| Effect of exchange rate on cash, cash equivalents and restricted cash | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of period | |||||
| Cash, cash equivalents and restricted cash at end of period | |||||
| Supplemental disclosure of cash flow information: | |||||
| Operating cash flows paid for operating lease | |||||
| Cash paid for interest | |||||
| Cash paid for income taxes | |||||
| Non-cash operating, investing and financing activities: | |||||
| Inventory purchases included in accrued liabilities | |||||
| Accrued milestone payments classified as intangible assets, net | |||||
| Right-of-use assets obtained in exchange for lease liabilities | |||||
| Decrease in ROU assets and lease liabilities due to lease modification | |||||
| Stock-based compensation capitalized to inventory | |||||
| Conversion of convertible notes, net into shares of common stock | |||||
| Issuance of common stock in connection with settlement of Contingent Milestone and Indemnification Holdback liabilities | |||||
| Contingent Milestone and Indemnification Holdback liabilities for common stock issuance in exchange for acquired intangible assets | |||||
| Issuance of common stock in exchange for acquired intangible | |||||
| Deferred tax liability incurred from acquired intangible | |||||
| Contingent milestone liability for common stock issuance for acquired intangible assets | |||||
| Indemnification Holdback liability for common stock issuance in exchange for acquired intangible assets | |||||
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