$OPK

$1.61 -$0.02 (1.23%) Close

$OPK Overview Financial Statements SEC Filings Executives News Red Flags Capital Raising Ownership Insider Transactions Congressional Trades

Ownership

13F as of Q2 2026 · 746.3M shares outstanding

Who owns OPK?

By type of holder

Institutions 27.0% Insiders 37.0% Everyone else 35.9%

Concentration Top 10 holders own 90.4%

Frost Phillip MD Et Al 34.2% · Frost Gamma Investments Trust 29.0%

Institutional ownership

27.0%

+0.1 pts vs last qtr

Institutional holders

219

-16 vs last qtr

Net shares bought

+614.0K

by institutions in Q2 2026

New / sold out

23 / 39

positions opened vs closed

How is ownership changing?

Institutions, last 8 quarters

Biggest buyers in Q2 2026

Highbridge Capital Management LLC NEW +3.6M
State Street Corp +807.7K

Biggest sellers in Q2 2026

UBS Group AG −1.1M
Jane Street Group, LLC −884.9K

Who is planning to sell?

No insider has filed a notice of proposed sale (Form 144) for OPKO Health, Inc. in the last 12 months.

Is your stake being diluted?

Diluted share count, FY2019–FY2025

+26.1%

+3.95% a year

Each share's claim on the business

−20.7%

shrank without buying or selling a share

Spent on buybacks vs paid in stock

$137M vs $87.5M

over 7 fiscal years

Diluted shares, split-adjusted

Buybacks Stock-based comp

How patient are the owners?

Institutional shares by how long they've been held

5+ years65% 3–5 years1% 1–3 years30% Under 1 year5%

Quarterly turnover

5.5%

of institutional shares changed hands

Top 10 managers, median time held

5 years

Super Investors

Investment managers reporting OPK on Form 13F

Holder	Shares	% of company	Change vs last qtr	Held since	% of their book
RC Rubric Capital Management LP	47.8M	6.40%	Unchanged	2024	0.7%
Shares held by quarter Peak holding48.7M (Q3'24) Change over 8 quarters−915.4K Share of the company6.400% Rubric Capital Management LP's full portfolio →
B BlackRock, Inc.	37.0M	4.95%	+746.7K (+2.1%)	≤2021	0.0%
Shares held by quarter Peak holding37.0M (Q2'26) Change over 8 quarters+8.4M Share of the company4.950% BlackRock, Inc.'s full portfolio →

Rubric Capital Management LP

47.8M

% of company

6.40%

Change vs last qtr

Unchanged

Held since

2024

BlackRock, Inc.

37.0M

% of company

4.95%

Change vs last qtr

+746.7K (+2.1%)

Held since

≤2021

28 more super investors behind a free account

See every manager holding OPKO Health, Inc., how their position has changed, and how long they've held it.

Institutional Funds

Mutual funds and ETFs reporting OPK on Form N-PORT; together they hold 9.9% of the company

Fund	Position value	Shares	% of company	% of the fund	As of
IR iShares Russell 2000 ETF iShares Trust	$15.7M	10.5M	1.40%	0.02%	June 30, 2026
VT Vanguard Total Stock Market Index Fund Vanguard Index Funds	$14.6M	9.8M	1.31%	0.00%	June 30, 2026

iShares Russell 2000 ETF

iShares Trust

Position value

$15.7M

% of company

1.40%

% of the fund

0.02%

As of

June 30, 2026

Vanguard Total Stock Market Index Fund

Vanguard Index Funds

Position value

$14.6M

% of company

1.31%

% of the fund

0.00%

As of

June 30, 2026

23 more funds behind a free account

See every fund holding OPKO Health, Inc. and how much of the fund the position is.

Insiders and 5%+ holders

From Forms 3/4/5 and Schedules 13D/G

Holder	Shares	% of company	Change vs last qtr	8 quarters	Held since	% of their book
FP Frost Phillip MD Et Al 5%+ holder 13D · 34.1%	255.4M	34.22%	—	—	—	—
This holder reports through Schedule 13D/G, not a quarterly 13F. Share of the company34.220% Disclosed stake13D · 34.1% View the 13D/G filing →
FG Frost Gamma Investments Trust 5%+ holder 13D · 29.0%	216.7M	29.04%	—	—	—	—
This holder reports through Schedule 13D/G, not a quarterly 13F. Share of the company29.040% Disclosed stake13D · 29.0% View the 13D/G filing →

Frost Phillip MD Et Al

5%+ holder13D · 34.1%

255.4M

% of company

34.22%

Change vs last qtr

—

Held since

—

Frost Gamma Investments Trust

5%+ holder13D · 29.0%

216.7M

% of company

29.04%

Change vs last qtr

—

Held since

—

6 more holders behind a free account

See every insider and 5%+ holder of OPKO Health, Inc..

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