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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows used in operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash provided by (used in) operating activities: | |||||
| Depreciation and amortization | |||||
| Sharebased compensation | |||||
| Amortization of premium and discount on marketable securities, net | |||||
| Loss on disposal of property and equipment | |||||
| Impairment of long-lived assets | |||||
| Other non-cash items | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets, and other assets | |||||
| Prepaid research and development | |||||
| Non-refundable sublicense and transition services payments received | |||||
| Right of use assets and operating lease liabilities | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Net cash provided by (used in) operating activities | |||||
| Cash flows provided by (used in) investing activities: | |||||
| Purchases of marketable securities | |||||
| Sales or maturities of marketable securities | |||||
| Purchases of property and equipment | |||||
| Purchases of property and equipment and other assets | |||||
| Sales of property and equipment and other assets | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows provided by (used in) financing activities: | |||||
| Proceeds from issuance of common stock under the ATM Facility, net of offering costs | |||||
| Proceeds from the exercise of stock options | |||||
| Proceeds from the issuance of common stock under employee stock purchase plan | |||||
| Net cash provided by (used in) financing activities | |||||
| Net increase (decrease) in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of year | |||||
| Cash and cash equivalents at end of year | |||||
| Supplemental disclosure of noncash activities: | |||||
| Unrealized gain (loss) on marketable securities | |||||
| Property and equipment in accounts payable and accrued expenses and other current liabilities | |||||
| Right of use assets recognized upon the commencement of sublease | |||||
| Operating lease liabilities recognized upon the commencement of sublease | |||||
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