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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Stock-based compensation | |||||
| Non-cash operating lease expense | |||||
| Impairment of in-process research and development intangible asset | |||||
| Accretion of discount on marketable debt securities | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Operating lease liabilities | |||||
| Deferred revenues | |||||
| Deferred tax liabilities | |||||
| Other | |||||
| Net cash used in operating activities | |||||
| Investing activities | |||||
| Cash acquired in acquisition of Apexigen, Inc. | |||||
| Redemption of marketable debt securities | |||||
| Purchase of marketable debt securities | |||||
| Purchase of property and equipment | |||||
| Net cash provided by (used in) investing activities | |||||
| Financing activities | |||||
| Proceeds from issuance of common stock and pre-funded warrants in private placement, net of offering costs | |||||
| Proceeds from issuance of common stock pursuant to ATM program, net of offering costs | |||||
| Tax withholding payments related to net settlement of restricted common stock | |||||
| Proceeds from the exercise of stock options | |||||
| Proceeds from the sale of stock under employee stock purchase plan | |||||
| Proceeds from issuance of common stock under ESPP | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of year | |||||
| Cash, cash equivalents and restricted cash at end of year | |||||
| Supplemental cash flow information: | |||||
| Cash paid for interest | |||||
| Cash paid for taxes | |||||
| Cash paid for income taxes | |||||
| Noncash investing and financing activities | |||||
| ROU asset in exchange for financing lease liability | |||||
| Shares, warrants, and replacement stock options and restricted stock units issued for acquisition of Apexigen, Inc. | |||||
| Property and equipment in accounts payable and accrued expenses | |||||
| Issuance of common stock to Pfizer Inc. | |||||
| Reconciliation of cash, cash equivalents and restricted cash: | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
| Total cash, cash equivalents and restricted cash shown in the statement of cash flows | |||||
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