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Arcus Biosciences, Inc. logo

Arcus Biosciences, Inc.

arcusbio.com

What Do They Do?

Develops investigational medicines for cancer and inflammatory and autoimmune diseases, working with pharmaceutical partners on development and commercialization.

How Do They Make Money?

Most revenue comes from partner licenses and development work: partners pay upfront and milestone fees for licenses, while research and development work earns payments as it is performed. The company has also received research support and reimbursement for clinical materials.

revenue
SegmentShareRevenue
License and development services
Mix

89%
Other Collaboration Revenue
11%
FY2022: 34%

Who Are Their Customers?

Arcus works directly with pharmaceutical partners: Gilead licenses several programs and shares development, while Taiho holds rights to programs in certain Asian markets.

Customers above 10% of revenue, FY2025
of revenue from one customer
FY2023: 96% from one customer

Do Revenues Turn Into Profits?

No. It lost $353M in FY2025.

Operating income, FY2025
−156% of revenue
▲ +17% (Loss) vs FY2024 (−$330M, −128%)
Net income, FY2025
−143% of revenue
▲ +25% (Loss) vs FY2024 (−$283M, −110%)
Free cash flow, FY2025
−196% of revenue
▲ +175% (Loss) vs FY2024 (−$176M, −68%)

How Are They Changing?

Since the FY2025 annual report
Latest quarter: Q2 FY2026, the three months to Jun 30, 2026
Revenue
▼ −74%
vs $160M in Q2 FY2025
Net income
vs $0 in Q2 FY2025
License and development services share of revenue vs 95.0% in Q2 FY2025
  • Apr 20, 2026 STAR-121 ended, and Gilead's options on additional pipeline programs will end Gilead will retain existing time-limited options to certain programs but will have no options on additional early-stage programs.

Shrinking. Revenue fell 36% in 4 years, from $383M in FY2021 to $247M in FY2025, about 10% a year.

Revenue over time
License and development services Other Collaboration Revenue License and Development Services Revenue
$500M$250M$0

Who Do They Compete With?

Competes with AstraZeneca, BeiGene, Bristol-Myer Squibb, GlaxoSmithKline, Merck, Novartis, Pfizer, Regeneron, Sanofi, Roche, Genentech, Celldex Therapeutics, Abbvie, Amgen, NiKang Therapeutics, Arrowhead Pharmaceuticals, I-MAB Biopharma, Incyte, Innate Pharma, and Innovent Biologics

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