Tectonic Therapeutic, Inc.
tectonictx.comWhat Do They Do?
Develops therapeutic proteins and antibodies aimed at cell-surface receptors for patients with pulmonary hypertension and hereditary hemorrhagic telangiectasia.
10-K for FY2025, filed Feb 26, 2026We are a clinical-stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate…View ↗
GPCRs are receptor molecules found on the surface of cells that act as sensors for various extracellular stimuli to enable communication…View ↗
Our lead asset, TX45, is an Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone relaxin. Relaxin…View ↗
Our second product candidate, TX2100, is a VHH-Fc fusion antagonist antibody that binds to the APJ receptor (also known as the apelin…View ↗
How Are They Changing?
From gene therapies to biologic medicines
The older report described gene therapies made from patients’ stem cells for rare genetic diseases. The latest describes therapeutic proteins and antibodies aimed at cell-surface receptors, including candidates for pulmonary hypertension and a genetic bleeding disorder.
10-K for FY2022, filed Mar 23, 2023 10-K for FY2025, filed Feb 26, 2026We are a clinical-stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate…View ↗
Our lead asset, TX45, is an Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone relaxin. Relaxin…View ↗
Our second product candidate, TX2100, is a VHH-Fc fusion antagonist antibody that binds to the APJ receptor (also known as the apelin…View ↗
Who Do They Compete With?
Competes with AstraZeneca, Vaderis, Terremoto, Atavistik, Diagonal Therapeutics, Alnylam Pharmaceuticals, Boehringer Ingelheim, Novartis, Septerna, SOSEI-Heptares, Structure Therapeutics, Abalone Bio, Orion Biotechnology, Abilitia Bio, Confo Therapeutic, Omeros, and GPCR Therapeutics
10-K for FY2025, filed Feb 26, 2026We face competition from companies that are pursuing development of engineered proteins or small molecule agonists of relaxin including…View ↗
Loading...
