Develops Niyad, a regional anticoagulant for dialysis circuits, and other medicines for use in medically supervised settings.
10-K for FY2025, filed Mar 23, 2026We are a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically…View ↗
Our portfolio is principally focused on our lead product candidate, Niyad (nafamostat mesylate), for use as a regional anticoagulant during…View ↗
We are developing Niyad to become the first and only FDA-approved regional anticoagulant for use in adult patients undergoing CRRT. Niyad…View ↗
$28K
10-K for FY2025, filed Mar 23, 2026
$28K ↗
Hospitals buy ready-to-use syringe presentations of these ingredients mainly from compounding facilities, or dilute products in-house. Talphera's Niyad sales work is pre-launch; a potential launch may use internal resources or a commercial partner.
10-K for FY2025, filed Mar 23, 2026
No. It lost $14.3M in FY2025.
10-K for FY2025, filed Mar 23, 2026
Narrower development focus
The earlier report described nafamostat and pre-filled syringe candidates as the portfolio. The latest centers development on Niyad and says the syringe candidates may be discontinued.
10-K for FY2022, filed Mar 31, 2023 10-K for FY2025, filed Mar 23, 2026
Second candidate's intended uses
The earlier report said the direct-infusion nafamostat candidate would initially target ARDS and DIC. The latest says Talphera is still evaluating its first indication, with DIC or acute pancreatitis among the possibilities.
10-K for FY2022, filed Mar 31, 2023 10-K for FY2025, filed Mar 23, 2026LTX-608 is our proprietary nafamostat formulation for direct IV infusion being explored as an investigational product for: (a) antiviral…View ↗
LTX-608 is our nafamostat formulation for direct IV infusion being explored as an investigational product for one or more of the following…View ↗
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