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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities | |||||
| Net Income Loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation, amortization and accretion | |||||
| Depreciation and amortization | |||||
| Accretion of discount and amortization of premium on purchase of debt securities | |||||
| Accretion of loan exit fee and amortization of loan costs, net | |||||
| Reduction in the carrying amount of operating lease right-of-use assets | |||||
| Stock-based compensation | |||||
| Issuance of Class A common stock for licensing payment, net of costs | |||||
| Change in fair value of non-marketable equity securities | |||||
| Payment of VT-109 license fee | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expense and other current assets | |||||
| Other assets | |||||
| Accounts payable | |||||
| Accrued and other liabilities | |||||
| Operating lease liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities | |||||
| Payment of VT-109 license fee | |||||
| Purchase of property and equipment | |||||
| Purchase of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Proceeds from sale of marketable securities | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows from financing activities | |||||
| Proceeds from exercise of stock options and employee stock purchase plan | |||||
| Proceeds from refinancing under loan and security agreement, net | |||||
| Payment of deferred issuance costs related to unfunded loan commitments | |||||
| Proceeds from short swing settlement | |||||
| Proceeds from borrowings, net of costs | |||||
| Repurchase of common stock | |||||
| Proceeds from issuance of common stock in follow-on offerings | |||||
| Payment of issuance costs and underwriting fees related to follow-on offerings | |||||
| Net cash provided by financing activities | |||||
| Net increase in cash and cash equivalents | |||||
| Cash and cash equivalents, beginning of year | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
| Total cash and cash equivalents, beginning of year | |||||
| Cash and cash equivalents, end of year | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
| Total cash and cash equivalents, end of year | |||||
| Supplemental disclosure of cash flow information | |||||
| Cash paid for interest expense | |||||
| Cash paid for operating leases | |||||
| Issuance of Class A common stock in payment of licensing fees | |||||
| Purchases of property and equipment included in accounts payable | |||||
| Follow-on offering costs included in accounts payable | |||||
| Follow-on offering costs included in accrued and other liabilities | |||||
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