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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation | |||||
| Amortization of acquired intangible assets | |||||
| Non-cash operating lease cost | |||||
| Stock-based compensation expense | |||||
| Amortization of deferred financing costs, debt discounts and premiums and discounts on available-for-sale marketable securities | |||||
| Change in fair value of preferred stock tranche liability | |||||
| Change in fair value of warrant liability | |||||
| Non-cash change in fair value of Notes | |||||
| Loss on debt extinguishment | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable, net | |||||
| Grant receivable | |||||
| Inventory | |||||
| Prepaid expenses, other current assets and other assets | |||||
| Accounts payable | |||||
| Accrued expenses and other liabilities | |||||
| Deferred liabilities | |||||
| Net cash used in operating activities | |||||
| Investing activities | |||||
| Purchases of property and equipment | |||||
| Purchases of intangible assets | |||||
| Purchases of investments | |||||
| Maturities of investments | |||||
| Net cash (used in) provided by investing activities | |||||
| Financing activities | |||||
| Proceeds from the issuance of common stock and pre-funded warrants, net | |||||
| Proceeds from the issuance of warrants | |||||
| Proceeds from issuance of Series B Convertible Preferred Stock, net | |||||
| Proceeds from exercise of warrants | |||||
| Proceeds from long-term debt | |||||
| Repayment of long-term debt | |||||
| Payments for loan amendment | |||||
| Repayment of 2018 Notes | |||||
| Proceeds from insurance premium financing | |||||
| Payments on insurance premium financing | |||||
| Proceeds from the exercise of stock options and employee stock purchase program | |||||
| Net cash provided by financing activities | |||||
| Increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of period | |||||
| Cash, cash equivalents and restricted cash at end of period | |||||
| Supplemental disclosure | |||||
| Cash paid for interest | |||||
| Cash paid for income tax expense | |||||
| Supplemental disclosure of non-cash investing and financing activities | |||||
| Issuance of preferred stock tranche liability | |||||
| Purchases of property and equipment included in accounts payable and accrued expenses | |||||
| Issuance costs included in accounts payable and accrued expenses | |||||
| Conversion of Series B Convertible Preferred Stock to common stock | |||||
| Conversion of warrant liability into additional paid-in capital upon warrant exercise | |||||
| Right of use asset obtained in exchange for operating lease liability | |||||
| Purchases of intangible asset in accounts payable and accrued expenses | |||||
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