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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net income (loss) | |||||
| Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: | |||||
| Depreciation and amortization | |||||
| Loss on disposal of property and equipment | |||||
| Amortization of discount on short-term investments, net | |||||
| Impairment of intangible assets | |||||
| Gain on modification of lease liability | |||||
| Stock-based compensation | |||||
| Gain on remeasurement of future royalty liability | |||||
| Non-cash interest expense related to sale of future royalties | |||||
| Non-cash revenue related to sale of future royalties | |||||
| Change in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Unbilled receivable from government contracts | |||||
| Prepaid expenses and other assets | |||||
| Prepaid clinical services, long-term | |||||
| Accounts payable | |||||
| Deferred revenue | |||||
| Grant | |||||
| Government Contract | |||||
| Collaboration Revenue | |||||
| Total deferred revenue | |||||
| Accrued liabilities | |||||
| Accrued and other liabilities | |||||
| Net cash provided by (used in) operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of property and equipment | |||||
| Proceeds from sale of property and equipment | |||||
| Purchases of investments | |||||
| Proceeds from maturities of investments | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from issuance of common stock upon exercise of warrants | |||||
| Shares acquired to settle employee tax withholding liabilities | |||||
| Proceeds from issuance of common stock upon exercise of stock options | |||||
| Proceeds from issuance of common stock under the employee stock purchase plan | |||||
| Proceeds from issuance of treasury stock under the employee stock purchase plan | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of the period | |||||
| Cash and cash equivalents at end of the period | |||||
| Operating lease liabilities arising from obtaining right-of-use assets | |||||
| Adjustment to operating lease right-of-use asset from lease modification | |||||
| Acquisition of property and equipment included in accounts payable and other accrued current liabilities | |||||
| Acquisition of property and equipment included in accounts payable and accrued expenses | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
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