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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flow from operating activities | |||||
| Net (loss) income | |||||
| Adjustments to reconcile net (loss) income to net cash (used in) provided by operating activities: | |||||
| Stock-based compensation expense | |||||
| Depreciation | |||||
| Impairment charge on leased facility | |||||
| Amortization of premiums and discounts on marketable securities | |||||
| Loss on disposal of fixed assets | |||||
| Non-cash lease expense | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Related party collaboration receivable | |||||
| Prepaid expenses and other assets | |||||
| Operating lease, right-of-use assets | |||||
| Accounts payable | |||||
| Accrued expenses | |||||
| Operating lease liabilities | |||||
| Deferred revenue | |||||
| Net cash (used in) provided by operating activities | |||||
| Cash flow from investing activities | |||||
| Purchases of property and equipment | |||||
| Purchases of marketable securities | |||||
| Proceeds from sales and maturities of marketable securities | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flow from financing activities | |||||
| Proceeds from the exercise of stock options | |||||
| Proceeds from the issuance of common stock and pre-funded warrants in connection with the underwritten public offering | |||||
| Proceeds from the issuance of common stock in connection with the 2023 Novartis Stock Purchase Agreement | |||||
| Proceeds from the issuance of common stock in connection with the 2023 Neurocrine Collaboration Agreement | |||||
| Proceeds from the purchase of common stock under ESPP | |||||
| Net cash provided by financing activities | |||||
| Net (decrease) increase in cash, cash equivalents, and restricted cash | |||||
| Cash, cash equivalents, and restricted cash beginning of period | |||||
| Cash, cash equivalents, and restricted cash end of period | |||||
| Supplemental disclosure of cash and non-cash activities | |||||
| Operating lease right-of-use asset obtained in exchange for operating lease liability | |||||
| Capital expenditures incurred but not yet paid | |||||
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