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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash provided by (used in) operating activities: | |||||
| Amortization of right-of-use assets | |||||
| Depreciation of property and equipment | |||||
| Share-based compensation expense | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Prepaid expenses | |||||
| Other assets | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Deferred revenue | |||||
| Operating lease liabilities | |||||
| Other non-current liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities | |||||
| Purchases of property and equipment | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities | |||||
| Proceeds from the issuance of ordinary shares as a part of the September 2024 Offering, net of offering costs | |||||
| Proceeds from issuance pre-funded warrants, net of offering costs | |||||
| September 2024 Offering | |||||
| December 2025 Offering | |||||
| Proceeds from issuance of ordinary shares pursuant to the GSK Collaboration Agreement | |||||
| Proceeds from issuance of ordinary shares pursuant to the at-the-market equity program, net | |||||
| Proceeds from the exercise of share options | |||||
| Proceeds from the ESPP | |||||
| Net cash provided by financing activities | |||||
| Effect of foreign exchange rates on cash | |||||
| Net increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of period | |||||
| Cash, cash equivalents and restricted cash, end of period | |||||
| Supplemental disclosure of cash flow information: | |||||
| Offering costs in accounts payable at period end | |||||
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