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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Non-cash interest (income) expense | |||||
| Stock-based compensation expense | |||||
| Change in fair value of common stock warrant liabilities | |||||
| Issuance costs allocated to common stock warrant liabilities | |||||
| Loss on disposal of property and equipment | |||||
| Changes in operating assets and liabilities: | |||||
| Collaboration and license agreement receivable | |||||
| Prepaid and other assets | |||||
| Operating lease right-of-use asset | |||||
| Accounts payable | |||||
| Accrued expenses and other liabilities | |||||
| Deferred revenue | |||||
| Operating lease liability | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of property and equipment | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from issuance of common stock | |||||
| At-The-Market Offerings | |||||
| Exercise of Prefunded Warrants | |||||
| Total proceeds from issuance of common stock | |||||
| Proceeds from issuance of prefunded warrants and common stock warrants in connection with a follow-on offering, net of issuance costs | |||||
| Proceeds from the issuance of common stock, prefunded warrants and liabilities to issue common stock in connection with the exercise of Series B warrants, net of issuance costs | |||||
| Proceeds from issuance of common stock under employee stock purchase plan | |||||
| Proceeds from exercise of stock options | |||||
| Proceeds from issuance of common stock and prefunded warrants in connection with the stock purchase agreement/private placement, net of issuance costs | |||||
| Gilead Stock Purchase Agreement | |||||
| Private Placement | |||||
| Proceeds from issuance of common stock in connection with at-the-market offering | |||||
| Repayments of debt principal | |||||
| Payments of finance lease | |||||
| Net cash provided by financing activities | |||||
| Increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of period | |||||
| Cash, cash equivalents and restricted cash, end of period | |||||
| Supplemental cash flow disclosure: | |||||
| Cash paid for interest | |||||
| Supplemental disclosure of non-cash activities: | |||||
| Transfer of finance lease asset to property and equipment | |||||
| Capital expenditures included in accounts payable or accrued expenses | |||||
| Issuance costs included in accounts payable or accrued expenses | |||||
| Reconciliation to amounts within the consolidated balance sheets: | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
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