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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities | |||||
| Net loss including noncontrolling interest | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Accretion of discount on marketable debt securities, net | |||||
| Stock-based compensation | |||||
| Gain on sale of marketable securities, net | |||||
| Change in fair value of marketable equity securities | |||||
| Addition of right-of-use asset | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
| Asset impairment charges | |||||
| Non-cash royalty revenue related to the sale of future royalties | |||||
| Non-cash interest expense on liabilities related to the sale of future royalties | |||||
| Equity received in connection with license agreement | |||||
| Equity received in connection with sale of financial assets | |||||
| Equity securities impairment | |||||
| Change in fair value of equity securities | |||||
| Impairment on equity securities | |||||
| Abandonment of capitalized intangibles | |||||
| Loss on disposal of assets | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Interest receivable from marketable debt securities | |||||
| Prepaid expenses and other assets | |||||
| Accounts payable | |||||
| Accrued expenses | |||||
| Income taxes | |||||
| Operating lease, net | |||||
| Deferred revenue | |||||
| Deferred income | |||||
| Other assets and liabilities, net | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities | |||||
| Proceeds from maturities of marketable debt securities available-for-sale | |||||
| Proceeds from sale of marketable debt securities available-for-sale | |||||
| Purchase of marketable debt securities | |||||
| Purchase of property and equipment | |||||
| Conversion of convertible note | |||||
| Exercise of stock options | |||||
| Purchase of patents | |||||
| Proceeds from sales of marketable equity securities | |||||
| Proceeds from sales and maturities of marketable debt securities | |||||
| Proceeds from sale of property and equipment | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows from financing activities | |||||
| Proceeds from the exercises of stock options | |||||
| Proceeds from issuance of common stock under the Employee Stock Purchase Plan | |||||
| Proceeds from issuance of common stock and pre-funded warrants | |||||
| Common stock and pre-funded warrants issuance costs | |||||
| Proceeds from the sale of future royalties | |||||
| Proceeds from noncontrolling interest | |||||
| Cash paid to acquire noncontrolling interest | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash, cash equivalents, and restricted cash | |||||
| Cash, cash equivalents, and restricted cash, beginning of period | |||||
| Cash, cash equivalents, and restricted cash, end of period | |||||
| Supplemental disclosure of cash flow information | |||||
| Interest paid | |||||
| Income taxes paid | |||||
| Unrealized loss on marketable securities | |||||
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