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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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FY2019
12 months to Dec 31, 2019
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FY2018
12 months to Dec 31, 2018
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|---|---|---|---|---|---|
| Operating activities: | |||||
| Net loss | |||||
| Non-cash adjustments reconciling net loss to operating cash flows | |||||
| Non-cash consideration earned from license agreement | |||||
| Change in fair value of long-term investment | |||||
| Depreciation of property and equipment | |||||
| Depreciation and amortization expense | |||||
| Amortization of premium and accretion of discounts on investments | |||||
| Share-based compensation expense | |||||
| Loss on disposal of fixed assets | |||||
| Foreign currency adjustments | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable, net | |||||
| Inventory | |||||
| Other current assets | |||||
| Other long-term assets | |||||
| Right-of-use asset | |||||
| Lease liability | |||||
| Accounts payable, accrued liabilities and other liabilities | |||||
| Cash flows used in operating activities | |||||
| Investing activities: | |||||
| Purchases of short-term investments | |||||
| Sales and maturities of short-term investments | |||||
| Purchases of property and equipment | |||||
| Cash flows provided by (used in) investing activities | |||||
| Financing activities: | |||||
| Proceeds from issuance of common stock, net of issuance costs | |||||
| Proceeds from issuance of common stock under equity incentive plans | |||||
| Proceeds from disgorgement of shareholders’ short-swing profits | |||||
| Proceeds from issuances under employee stock purchase plan | |||||
| Cash flows provided by financing activities | |||||
| Cash and cash equivalents | |||||
| (Decrease) increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of year | |||||
| Cash, cash equivalents and restricted cash, end of year | |||||
| Supplemental disclosures of non-cash investing activities: | |||||
| Accrued capital expenditures | |||||
| Capitalized intangible asset included in accrued liabilities | |||||
| Allowance utilized for tenant improvements | |||||
| Initial recognition of operating right-of-use asset | |||||
| Initial recognition of operating lease liability | |||||
| Reconciliation of cash, cash equivalents and restricted cash, end of year: | |||||
| Cash and cash equivalents | |||||
| Restricted cash included in other long-term assets | |||||
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