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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation | |||||
| Stock-based compensation expense | |||||
| Amortization of premiums and discounts on marketable securities, net | |||||
| Loss on disposal of property and equipment | |||||
| Noncash operating lease costs | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid and other assets | |||||
| Accounts payable and accrued liabilities | |||||
| Accrued compensation | |||||
| Accounts payable | |||||
| Accrued expenses and other liabilities | |||||
| Operating right-of-use assets and lease liabilities, net | |||||
| Deferred revenue | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities | |||||
| Purchases of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Purchases of property and equipment | |||||
| Tenant improvements capitalized to right-of-use assets | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities | |||||
| Proceeds from exercise of stock/unit options, net of repurchases | |||||
| Proceeds from issuance of common stock in public offerings, net of issuance costs | |||||
| Proceeds from issuance of common stock in private placements, net of issuance costs and allocation to deferred revenues (Note 5) | |||||
| Proceeds from issuance of pre-funded warrants in a private placement, net of issuance costs | |||||
| Proceeds from the issuance of common stock under employee incentive equity plans | |||||
| Payments for taxes related to net share settlement of equity awards | |||||
| Net cash provided by financing activities | |||||
| Effect of exchange rate on cash, cash equivalents and restricted cash | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of period | |||||
| Cash, cash equivalents and restricted cash at end of period | |||||
| Supplemental schedule of noncash investing and financing activities: | |||||
| Right-of-use assets obtained in exchange for operating lease liabilities | |||||
| Costs incurred, but not paid, in connection with purchases of property and equipment included in accounts payable and accrued expenses and other liabilities | |||||
| Tenant improvements capitalized to right-of-use assets within accounts payable and accrued expenses and other liabilities | |||||
| Receivables from stock option exercises included in prepaid and other current assets | |||||
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