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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Stock-based compensation | |||||
| Net accretion of investments in marketable debt securities | |||||
| Non-cash rent expense | |||||
| Deferred income tax expense | |||||
| Loss on disposal of property and equipment | |||||
| Realized gain on investments in marketable debt securities | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable from collaboration | |||||
| Prepaid expenses and other current assets | |||||
| Other assets | |||||
| Accounts payable | |||||
| Accrued research and development expenses | |||||
| Other accrued expenses | |||||
| Deferred revenue from a related party | |||||
| Operating lease liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities | |||||
| Proceeds from maturities of marketable securities | |||||
| Purchases of marketable securities | |||||
| Proceeds from sale of property and equipment | |||||
| Purchases of property and equipment | |||||
| Proceeds from sale of marketable securities | |||||
| Proceeds from the sale of Microbiome assets | |||||
| Net cash (used in) provided by investing activities | |||||
| Cash flows from financing activities | |||||
| Proceeds from the issuance of common stock to a related party, net of issuance costs | |||||
| Proceeds from the issuance of common stock, pre-funded warrants and warrants in an underwritten offering, net of issuance costs | |||||
| Proceeds from the issuance of common stock and warrants in private placements to a related party, net of issuance costs | |||||
| Proceeds from the exercise of warrants | |||||
| Proceeds from the issuance of common stock under ATM equity offering program, net of issuance costs | |||||
| Proceeds from the issuance of common stock under ESPP | |||||
| Proceeds from the exercise of stock options | |||||
| Proceeds from the issuance of common stock and warrants in a registered direct offering, net of issuance costs | |||||
| Net cash provided by financing activities | |||||
| Net increase in cash and cash equivalents | |||||
| Cash and cash equivalents at the beginning of the year | |||||
| Cash and cash equivalents at the end of the year | |||||
| Supplemental non-cash investing and financing activities | |||||
| Operating lease liabilities arising from obtaining ROU assets | |||||
| Income taxes paid | |||||
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