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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net income (loss) | |||||
| Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: | |||||
| Depreciation and amortization | |||||
| Inventory obsolescence | |||||
| Stock-based compensation expense | |||||
| Non-cash interest expense on royalty financing obligations and secured term loan and amortization of debt issuance costs | |||||
| Equity modification associated with sale of BioCryst Ireland | |||||
| Mark-to-market adjustment on share-based liability | |||||
| Payment of Pharmakon PIK Interest | |||||
| Non-cash interest expense on royalty financing obligations | |||||
| Non-cash interest expense on secured term loan and amortization of debt issuance costs | |||||
| Amortization of discount on investments, net | |||||
| Loss on extinguishment of debt | |||||
| Loss on impairment | |||||
| Gain on sale of non-financial asset | |||||
| Gain on sale of BioCryst Ireland | |||||
| Changes in operating assets and liabilities: | |||||
| Increase in receivables | |||||
| Increase in inventory | |||||
| (Increase) decrease in prepaid expenses and other assets | |||||
| Decrease in royalty financing obligations | |||||
| Increase in accounts payable and accrued expenses | |||||
| Interest payable | |||||
| Decrease in deferred revenue | |||||
| Net cash provided by (used in) operating activities | |||||
| Cash flows from investing activities: | |||||
| Acquisitions of property and equipment | |||||
| Purchases of investments | |||||
| Sales and maturities of investments | |||||
| Sale of non-financial asset | |||||
| Proceeds from sale of BioCryst Ireland, net of cash divested | |||||
| Net cash (used in) provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Net proceeds from common stock issued under stock-based compensation plans | |||||
| Withholding taxes paid on stock-based awards | |||||
| Common stock issued to directors in lieu of cash retainer | |||||
| Net proceeds from term loans | |||||
| Repayment of principal on term loans | |||||
| Prepayment premium and fees on term loans | |||||
| Payment of debt issuance costs on Pharmakon Tranche A term loan | |||||
| Principal payments on royalty financing obligations | |||||
| Payment of royalty release fees | |||||
| Principal payments on finance lease liabilities | |||||
| Net proceeds from royalty financing liabilities | |||||
| Net cash (used in) provided by financing activities | |||||
| Effect of exchange rates on cash, cash equivalents and restricted cash | |||||
| Decrease in cash, cash equivalents and restricted cash | |||||
| Beginning of year | |||||
| End of year | |||||
| Supplemental cash flow disclosure: | |||||
| Cash paid for interest | |||||
| Cash paid for taxes | |||||
| Taxes withheld on stock-based awards included in accrued expenses | |||||
| Capitalized software costs included in accrued expenses | |||||
| Reconciliation of cash, cash equivalents and restricted cash: | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
| Restricted cash in other assets | |||||
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