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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating activities: | |||||
| Net (loss) income | |||||
| Adjustments to reconcile net (loss) income to net cash provided by (used in) operating activities: | |||||
| Stock-based compensation | |||||
| Asset impairments and write-downs | |||||
| Impairment of intangible asset and associated construction in progress | |||||
| Depreciation and amortization | |||||
| Amortization of right-of-use assets | |||||
| Unrealized loss on long-term marketable equity securities | |||||
| Realized gain on sale of long-term marketable equity securities, net | |||||
| Loss on disposal of asset | |||||
| Gain on settlement of obligation and recovery of written-off investment | |||||
| Revaluation of common stock warrant liability to estimated fair value | |||||
| Revaluation of contingent consideration to estimated fair value | |||||
| Other non-cash items | |||||
| Amortization of premium and accretion of discount on marketable securities, net | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Inventory | |||||
| Prepaid and other assets | |||||
| Accounts payable | |||||
| Accrued compensation | |||||
| Accrued and other liabilities | |||||
| Accrued royalties | |||||
| Operating lease liabilities, net | |||||
| Refund liability - CMS advance payment | |||||
| Deferred taxes | |||||
| Net cash provided by (used in) operating activities | |||||
| Investing activities: | |||||
| Maturities of marketable securities | |||||
| Purchases of short-term marketable securities | |||||
| Purchases of marketable securities | |||||
| Purchase of corporate equity securities | |||||
| Sale of corporate equity securities | |||||
| Additions of capital expenditures | |||||
| Acquisition of intangible assets | |||||
| Acquisition of business, net of cash acquired | |||||
| Net cash provided by (used in) investing activities | |||||
| Financing activities: | |||||
| Proceeds from issuance of common shares | |||||
| Total proceeds from issuance of common shares | |||||
| Payment of contingent consideration | |||||
| Principal payments on finance lease obligations | |||||
| Repurchase and retirement of common stock | |||||
| Proceeds from exercise of warrants | |||||
| Proceeds from exercise of stock options | |||||
| Proceeds from issuance of common stock under employee stock purchase plan | |||||
| Taxes paid related to net share settlement of restricted stock units | |||||
| Net cash used in financing activities | |||||
| Effect of exchange rate changes on cash and cash equivalents | |||||
| Net (decrease) increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents, and restricted cash at beginning of period | |||||
| Cash, cash equivalents, and restricted cash at end of period | |||||
| Supplemental disclosures of cash information | |||||
| Cash paid for interest | |||||
| Cash paid for income taxes | |||||
| Supplemental disclosures of non-cash operating, investing and financing information | |||||
| Shares issued in lieu of payment | |||||
| Operating lease right-of-use assets | |||||
| Purchases of capital expenditures in accounts payable and accrued liabilities | |||||
| Employee stock purchase plan shares included in accrued compensation | |||||
| Contingent consideration | |||||
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