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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Non-cash lease expense | |||||
| Stock-based compensation expense | |||||
| Non-cash activity related to the sale of future royalties prior to the sale of Erivedge | |||||
| Gain on release of liability related to sale of future royalties associated with sale of assets | |||||
| Amortization of premiums and discounts on investments | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Prepaid expenses and other assets | |||||
| Accounts payable and accrued and other liabilities | |||||
| Operating lease liability | |||||
| Total adjustments | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of investments | |||||
| Sales and maturities of investments | |||||
| Purchases of property and equipment | |||||
| Proceeds from the sale of Erivedge | |||||
| Net cash provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from issuance of common stock, pre-funded warrants, and common warrants, net of issuance costs | |||||
| Total proceeds from issuance of common stock, pre-funded warrants, and common warrants, net of issuance costs | |||||
| Payment of liability of future royalties, net of imputed interest | |||||
| Net cash provided by financing activities | |||||
| Net decrease in cash and cash equivalents and restricted cash | |||||
| Cash and cash equivalents and restricted cash, beginning of period | |||||
| Cash and cash equivalents and restricted cash, end of period | |||||
| Supplemental cash flow data: | |||||
| Issuance costs in accounts payable | |||||
| Cash paid for interest | |||||
| Increase in right-of-use assets and operating lease liabilities resulting from lease modification | |||||
| Reconciliation of cash, cash equivalents and restricted cash: | |||||
| Cash and cash equivalents | |||||
| Restricted cash, long-term | |||||
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