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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization | |||||
| Stock-based compensation expense | |||||
| Net accretion of discounts on marketable securities | |||||
| Non-cash adjustment to operating lease expense | |||||
| Right-of-use asset amortization for finance lease | |||||
| Non-cash gain from divestiture of small molecule programs | |||||
| Other non-cash items | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Other non-current assets | |||||
| Accounts payable | |||||
| Accruals and other current liabilities | |||||
| Contract liabilities | |||||
| Related party contract liability | |||||
| Deferred research and development funding liability | |||||
| Other non-current liabilities | |||||
| Net cash used in operating activities | |||||
| Investing activities | |||||
| Maturities of marketable securities | |||||
| Purchases of marketable securities | |||||
| Purchases of property and equipment | |||||
| Net cash provided by (used in) investing activities | |||||
| Financing activities | |||||
| Proceeds from issuance of common stock and pre-funded warrants, net of issuance costs of $480 | |||||
| Proceeds from issuance / public offering of common stock and pre-funded warrants, net of issuance costs of | |||||
| Initial Closing | |||||
| Public Offering | |||||
| Total proceeds from issuance / public offering of common stock and pre-funded warrants, net of issuance costs of | |||||
| Proceeds from exercise of awards under equity incentive plans | |||||
| Payments for finance lease right-of-use asset | |||||
| Issuance costs related to the royalty financing | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of year | |||||
| Cash, cash equivalents and restricted cash at end of year | |||||
| Supplemental disclosures of cash flow information | |||||
| Equity consideration received in the divestiture of small molecule programs (Note 13) | |||||
| Increase in right-of-use asset due to lessor assets | |||||
| Right-of-use asset obtained in exchange for new finance lease liabilities | |||||
| Property and equipment purchases accrued but not yet paid | |||||
| Cash paid for finance lease interest | |||||
| Issuance costs incurred but not yet paid | |||||
| Cash paid during the year for income taxes | |||||
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