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About Generation Bio Co.
Generation Bio Co. is a genetic medicine company, which focuses on creating a new class of gene therapy to provide durable and redosable treatment for patients suffering from both rare and prevalent diseases. The company is headquartered in Cambridge, Massachusetts and currently employs 174 full-time employees. The company went IPO on 2020-06-12. The firm is innovating non-viral genetic medicines to provide durable, redosable treatments for hundreds of millions of patients living with rare and prevalent diseases. The firm is developing two distinct and complementary platforms: a potent, highly selective cell-targeted lipid nanoparticle (ctLNP) delivery system and a novel immune-quiet DNA (iqDNA) cargo produced by a scalable capsid-free manufacturing process that uses proprietary cell-free rapid enzymatic synthesis (RES). The firm is advancing a portfolio of programs guided by the potent and highly selective delivery of messenger ribonucleic acid (mRNA) and/or iqDNA using its ctLNP delivery system to target T cells, hematopoietic stem cells (HSCs), and hepatocytes, and intend to expand to additional tissues and cell types. Its work in T cells focuses on in vivo reprogramming of this cell type to treat cancer and autoimmune diseases.
Industry: Pharmaceutical Preparations Peers: Aadi Bioscience, Inc. Arbutus Biopharma Corp AVEO PHARMACEUTICALS, INC. Vaxart, Inc. BioAtla, Inc. GreenLight Biosciences Holdings, PBC SUTRO BIOPHARMA, INC. Immuneering Corp Poseida Therapeutics, Inc.
