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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Stock-based compensation expense | |||||
| Depreciation and amortization | |||||
| Amortization of debt discount | |||||
| Amortization of debt issuance costs | |||||
| Accretion of discount on short-term investments | |||||
| Realized gain on available-for-sale investments | |||||
| Retirement and impairment of property and equipment | |||||
| (Gain)/Loss on disposal of property and equipment | |||||
| Loss on extinguishment of debt | |||||
| Change in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Inventory | |||||
| Prepaid expenses and other assets | |||||
| Accounts payable | |||||
| Accrued clinical and manufacturing liabilities | |||||
| Accrued payroll and employee liabilities | |||||
| Other accrued liabilities | |||||
| Net cash used in operating activities | |||||
| Investing activities: | |||||
| Purchases of short-term investments | |||||
| Maturities and sales of short-term investments | |||||
| Purchases of property and equipment | |||||
| Proceeds from the sale of property and equipment | |||||
| Net cash provided by investing activities | |||||
| Financing activities: | |||||
| Net proceeds from the sale of common stock | |||||
| Net proceeds from notes financing | |||||
| Proceeds from sale of Series A Convertible Preferred Stock | |||||
| Cash paid for convertible notes extinguishment | |||||
| Cash paid for notes extinguishment | |||||
| Net proceeds from convertible note issuance | |||||
| Net proceeds from notes issuance | |||||
| Proceeds from warrant exercises | |||||
| Proceeds from purchases under the Employee Stock Purchase Plan | |||||
| Receipts (payments) for stock issued under the equity incentive plan | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of year | |||||
| Cash and cash equivalents at end of year | |||||
| Supplemental disclosure of cash flow information: | |||||
| Interest paid | |||||
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