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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization expense | |||||
| Non-cash lease expense | |||||
| Non-cash interest income on marketable securities | |||||
| Stock-based compensation expense, including employee stock purchase plan expense | |||||
| Loss on disposal of equipment | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Other assets and long-term deposits | |||||
| Accounts payable | |||||
| Other current liabilities | |||||
| Operating lease liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchase of equipment | |||||
| Disposal of fixed assets | |||||
| Maturities of marketable securities | |||||
| Purchases of marketable securities | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from issuance of shares upon follow-on public offering, net of issuance costs of $13,110 | |||||
| Proceeds from issuance of shares under at-the-market offering, net of issuance costs of $166 | |||||
| Proceeds from 2024 private placement, net of issuance costs of $6,498 | |||||
| Payment of issuance costs for shares issued under 2024 private placement | |||||
| Proceeds from borrowings under Credit Facility (Note 13) | |||||
| Proceeds from exercise of stock options | |||||
| Proceeds from issuance of common stock under employee stock purchase plan | |||||
| Net cash provided by financing activities | |||||
| Net (decrease) increase in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of period | |||||
| Cash and cash equivalents at end of period | |||||
| Issuance costs for equity private placement not paid in cash by the end of period | |||||
| Supplemental disclosure of cash flow information | |||||
| Exchange common stock shares for pre-funded warrants | |||||
| Research and development project deposit applied against final study invoices | |||||
| Right-of-use asset obtained in exchange for operating lease liabilities | |||||
| Unpaid issuance costs related to follow-on offering and 2024 private placement | |||||
| Research and development project deposit applied against study invoices | |||||
| System implementation cost included in other current liabilities | |||||
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