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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation expense | |||||
| Stock-based compensation expense | |||||
| Non-cash operating lease expense | |||||
| Amortization of premiums and discounts on marketable securities, net | |||||
| Non-cash collaboration and license agreement expense | |||||
| Other non-cash adjustments | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Accounts payable | |||||
| Accrued expenses | |||||
| Operating lease liabilities | |||||
| Deferred revenue | |||||
| Other | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of property and equipment | |||||
| Purchases of marketable securities | |||||
| Maturities of marketable securities | |||||
| Net cash (used in) provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Payment of issuance costs for at-the-market offerings | |||||
| Payments of tax withholdings related to vesting of restricted stock units | |||||
| Proceeds from exercise of options and employee stock purchase plan purchases | |||||
| Net cash provided by financing activities | |||||
| Increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of period | |||||
| Cash, cash equivalents and restricted cash, end of period | |||||
| Offering costs from follow-on public offering included in accounts payable | |||||
| Follow-On Offering | |||||
| At-The-Market Offering | |||||
| Supplemental disclosures of non-cash activities: | |||||
| Offering costs from in accounts payable / accrued expenses | |||||
| Follow-On Offering | |||||
| At-The-Market Offering | |||||
| Reconciliation of cash, cash equivalents and restricted cash: | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
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