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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Stock-based compensation expense | |||||
| Depreciation and amortization | |||||
| Non-cash interest expense | |||||
| Non-cash accretion & amortization of short-term investments | |||||
| Non-cash rent expense | |||||
| Change in fair value of embedded derivative liability | |||||
| Gain on settlement of forward contract | |||||
| Acquired IPR&D assets classified as investing activities | |||||
| Other non-cash items | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Inventory | |||||
| Prepaid expenses and other current assets | |||||
| Deferred revenue | |||||
| Other long-term assets, net | |||||
| Accounts payable, accrued expenses and other liabilities | |||||
| Net cash used in operating activities | |||||
| Investing activities | |||||
| Purchases of short-term investments | |||||
| Maturities of short-term investments | |||||
| Acquisition of IPR&D assets | |||||
| Purchases of property and equipment | |||||
| Net cash used in investing activities | |||||
| Financing activities | |||||
| Repayment of deferred royalty obligation | |||||
| Proceeds from issuance of common stock upon completion of public offering, net of offering costs | |||||
| Proceeds from the exercise of stock options | |||||
| Proceeds from issuance of common stock from ESPP | |||||
| Proceeds from royalty financing agreement, net of issuance costs | |||||
| Gain on settlement of forward contract | |||||
| Proceeds from Series A Preferred Stock, net of issuance costs | |||||
| Net cash provided by financing activities | |||||
| Effect of exchange rates on cash | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of period | |||||
| Cash, cash equivalents and restricted cash at end of period | |||||
| Supplemental disclosure of non-cash investing and financing activities: | |||||
| Non-current liability issued in exchange for the acquisition of IPR&D | |||||
| Issuance of common stock in exchange for IPR&D | |||||
| Accretion of preferred stock dividends | |||||
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