Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.
Reported portfolio value by quarter (8 quarters reported)
$149M in Q4 2019 → — now. Hover for any quarter.
As reported for the quarter ended September 30, 2021. Activity is the change in share count since the prior quarter's filing.
| Holding | % of portfolio | Activity | Shares | Value |
|---|---|---|---|---|
| 0 0 | NaN% | New | 0 | — |
What changed each quarter, from the filings' own share counts. Largest moves first; most recent 7 quarters.
quarter ended September 30, 2021 · filed November 15, 2021
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Biocryst Pharmaceuticals Inc | Exited | −864,916 | −$13.7M | — |
| Intellia Therapeutics Inc | Exited | −63,634 | −$10.3M | — |
| E Epizyme Inc | Exited | −836,802 | −$6.95M | — |
| Essa Pharma Inc | Exited | −237,442 | −$6.78M | — |
| Neogenomics Inc | Exited | −147,921 | −$6.68M | — |
| MP Mei Pharma Inc | Exited | −2,331,313 | −$6.64M | — |
| CP Crinetics Pharmaceuticals In | Exited | −294,620 | −$5.55M | — |
| Cytokinetics Inc | Exited | −244,673 | −$4.84M | — |
| Amicus Therapeutics Inc | Exited | −500,000 | −$4.82M | — |
| HB Harmony Biosciences Hldgs In | Exited | −150,000 | −$4.23M | — |
Showing the 10 largest of 23 changes.
quarter ended June 30, 2021 · filed August 16, 2021
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Protalix Biotherapeutics Inc | Exited | −2,125,585 | −$9.48M | — |
| Ptc Therapeutics Inc | Exited | −160,372 | −$7.59M | — |
| TP Turning Point Therapeutics I | Trimmed | −70,000 | −$5.47M | 0.2% |
| Amicus Therapeutics Inc | New | +500,000 | +$4.82M | 4.8% |
| CT Cara Therapeutics Inc | Exited | −180,000 | −$3.91M | — |
| Fulcrum Therapeutics Inc | Exited | −319,819 | −$3.77M | — |
| T Tricida Inc | Exited | −658,877 | −$3.49M | — |
| Apellis Pharmaceuticals Inc | Exited | −80,727 | −$3.46M | — |
| Verastem Inc | New | +705,585 | +$2.87M | 2.9% |
| E Epizyme Inc | Added | +272,247 | +$2.26M | 7.0% |
Showing the 10 largest of 16 changes.
quarter ended March 31, 2021 · filed May 17, 2021
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| IB Iveric Bio Inc | Exited | −1,388,136 | −$9.59M | — |
| Essa Pharma Inc | New | +237,442 | +$6.9M | 5.6% |
| Insmed Inc | Exited | −154,562 | −$5.15M | — |
| HB Harmony Biosciences Hldgs In | New | +150,000 | +$4.96M | 4.0% |
| Aurinia Pharmaceuticals Inc | Exited | −336,384 | −$4.65M | — |
| FT Frequency Therapeutics Inc | Exited | −124,650 | −$4.4M | — |
| CT Cara Therapeutics Inc | New | +180,000 | +$3.91M | 3.2% |
| T Tricida Inc | New | +658,877 | +$3.49M | 2.8% |
| E Epizyme Inc | Trimmed | −365,912 | −$3.19M | 4.0% |
| Geron Corp | New | +1,912,673 | +$3.02M | 2.4% |
Showing the 10 largest of 30 changes.
quarter ended December 31, 2020 · filed February 12, 2021
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| AT Aimmune Therapeutics Inc | Exited | −332,546 | −$11.5M | — |
| Protalix Biotherapeutics Inc | New | +2,470,332 | +$8.97M | 6.8% |
| Biocryst Pharmaceuticals Inc | New | +1,105,673 | +$8.24M | 6.3% |
| Orthopediatrics Corp | Exited | −171,607 | −$7.88M | — |
| Anaptysbio Inc | Exited | −330,549 | −$4.88M | — |
| Inozyme Pharma Inc | New | +170,796 | +$3.53M | 2.7% |
| Intellia Therapeutics Inc | New | +64,079 | +$3.49M | 2.7% |
| Assembly Biosciences Inc | Exited | −200,000 | −$3.29M | — |
| Regenxbio Inc | Exited | −116,405 | −$3.2M | — |
| Mirum Pharmaceuticals Inc | New | +161,628 | +$2.82M | 2.2% |
Showing the 10 largest of 33 changes.
quarter ended September 30, 2020 · filed November 13, 2020
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| AC Avrobio Inc Com | Exited | −225,900 | −$3.94M | — |
| Assembly Biosciences Inc | New | +200,000 | +$3.29M | 2.6% |
| AB Adverum Biotechnologies Inc Com | Exited | −156,012 | −$3.26M | — |
| T Tricida Inc | New | +188,182 | +$1.71M | 1.3% |
| G1 Therapeutics Inc | Trimmed | −145,279 | −$1.68M | 2.1% |
| Aurinia Pharmaceuticals Inc | Added | +105,945 | +$1.56M | 4.2% |
| FT Frequency Therapeutics Inc | Trimmed | −69,776 | −$1.34M | 2.0% |
| E Epizyme Inc | Added | +111,251 | +$1.33M | 9.4% |
| Z Zogenix Inc | Trimmed | −30,811 | −$553K | 0.6% |
| Ptc Therapeutics Inc | Trimmed | −5,841 | −$273K | 6.4% |
Showing the 10 largest of 21 changes.
quarter ended June 30, 2020 · filed August 14, 2020
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| AT Adc Therapeutics Sa Shs Isin#ch0499880968 | New | +134,912 | +$6.32M | 4.4% |
| FT Fulcrum Therapeutics Inc Com | New | +291,645 | +$5.33M | 3.7% |
| AT Aimmune Therapeutics Inc Com | Added | +220,000 | +$3.68M | 3.9% |
| Cytomx Therapeutics Inc | Exited | −482,982 | −$3.46M | — |
| CT Cara Therapeutics Inc | Exited | −258,766 | −$3.29M | — |
| T Tricida Inc | Exited | −131,661 | −$2.78M | — |
| IC Insmed Inc Com Par 01 | Added | +100,000 | +$2.75M | 3.2% |
| MB Merus B V Com Isin#nl0011606264 | New | +140,176 | +$2.26M | 1.6% |
| Xenon Pharmaceuticals Inc | Exited | −200,000 | −$2.11M | — |
| YT Y-mabs Therapeutics Inc Com | Trimmed | −48,763 | −$2.11M | 3.7% |
Showing the 10 largest of 26 changes.
quarter ended March 31, 2020 · filed May 14, 2020
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| A Arqule Inc | Exited | −595,018 | −$11.9M | — |
| Ascendis Pharma A/s | Exited | −43,775 | −$6.09M | — |
| Deciphera Pharmaceuticals Inc | Exited | −59,818 | −$3.72M | — |
| Cytokinetics Inc | New | +318,273 | +$3.61M | 3.6% |
| Regenxbio Inc | New | +115,000 | +$3.54M | 3.5% |
| A Avrobio Inc | New | +225,900 | +$3.27M | 3.2% |
| TP Turning Pt Therapeutics Inc | New | +77,172 | +$3.25M | 3.2% |
| Us Physical Therapy Inc | Exited | −21,500 | −$2.46M | — |
| DP Dicerna Pharmaceuticals Inc | Exited | −104,047 | −$2.29M | — |
| Xenon Pharmaceuticals Inc | New | +200,000 | +$2.11M | 2.1% |
Showing the 10 largest of 37 changes.
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