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About Actuate Therapeutics Inc
Actuate Therapeutics Inc is a US-based company operating in Biotechnology industry. The company is headquartered in Fort Worth, Texas and currently employs 6 full-time employees. The company went IPO on 2024-08-13. Actuate Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The firm is focused on developing therapies for the treatment of high impact, difficult to treat cancers through the inhibition of glycogen synthase kinase-3 (GSK-3). The firm is developing elraglusib, a small molecule that is designed to enter cancer cells and block the function of the enzyme GSK-3b, a master regulator of complex biological signaling cascades, including those mediated by oncogenes, that lead to tumor cell survival, growth, migration, and invasion. Its lead program, Elraglusib Injection, is an intravenous solution of elraglusib for the treatment of metastatic pancreatic ductal adenocarcinoma (mPDAC). Elraglusib Injection has been evaluated in a Phase I dose escalation study (Actuate-1801 Part 1) in 238 adult patients. Elraglusib is designed to act as a mediator of anti-tumor immunity through the inhibition of NF-kB and regulates multiple immune checkpoints and immune cell function.
Industry: Pharmaceutical Preparations Peers: Fennec Pharmaceuticals Inc Lineage Cell Therapeutics Inc Cibus Inc DiaMedica Therapeutics Inc Galectin Therapeutics Inc Generation Bio Co Inovio Pharmaceuticals Inc Sangamo Therapeutics Inc Shattuck Labs Inc
