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Super Investors ORACLE INVESTMENT MANAGEMENT INC
OI

ORACLE INVESTMENT MANAGEMENT INC

Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.

Portfolio value
$168M
Positions
22
Quarter ended
December 31, 2025
Filed
February 18, 2026

Reported portfolio value by quarter (51 quarters reported)

$876M $103M
Q2 13 Q1 16 Q4 18 Q3 21 Q2 24 Q4 25

$580M in Q2 2013 → $168M now. Hover for any quarter.

Holdings

As reported for the quarter ended December 31, 2025. Activity is the change in share count since the prior quarter's filing.

Holding % of portfolio Activity Shares Value
Genedx Holdings Corp 68.5% Trimmed 0.6% 884,654 $115M
Ardelyx Inc 6.5% Added 25% 1,872,624 $10.9M
Biohaven Ltd 5.2% Added 4.4% 772,181 $8.72M
Teladoc Health Inc Call 2.7% Added 38% 650,000 $4.55M
Novavax Inc Call 2.4% New 600,000 $4.03M
Ardelyx Inc Call 2.1% Trimmed 5.2% 600,000 $3.5M
Quidelortho Corp 2.0% Unchanged 118,291 $3.38M
Forian Inc 1.7% Unchanged 1,366,107 $2.9M
Personalis Inc 1.6% Added 48% 339,343 $2.7M
Biohaven Ltd Call 1.6% Trimmed 15% 232,900 $2.63M
Teladoc Health Inc 1.5% Trimmed 50% 354,338 $2.48M
Taysha Gene Therapies Inc 0.9% New 265,000 $1.46M
Cava Group Inc 0.6% Unchanged 17,100 $1M
Edgewise Therapeutics Inc 0.6% New 38,343 $951K
DO Day One Biopharmaceuticals I 0.6% New 100,000 $932K
Pfizer Inc Call 0.4% New 25,000 $623K
AE Ark ETF Tr 0.3% New 19,500 $565K
Sangamo Therapeutics Inc 0.3% Added 3.1% 1,035,742 $435K
Biogen Inc 0.3% Unchanged 2,412 $424K
Tempus Ai Inc 0.2% New 6,507 $384K
Tesla Inc 0.1% Unchanged 500 $225K
HG Hertz Global Hldgs Inc 0.0% New 15,000 $77.1K

Timeline of changes

What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.

Q4 2025

quarter ended December 31, 2025 · filed February 18, 2026

Company Action Shares changed Value of change % of portfolio
Novavax Inc Exited −635,000 −$5.51M —
Palantir Technologies Inc Exited −29,500 −$5.38M —
Novavax Inc New +600,000 +$4.03M 2.4%
CD Centene Corp Del Exited −110,300 −$3.94M —
Teladoc Health Inc Trimmed −351,078 −$2.46M 1.5%
Ardelyx Inc Added +368,798 +$2.15M 6.5%
Novavax Inc Exited −243,000 −$2.11M —
Taysha Gene Therapies Inc New +265,000 +$1.46M 0.9%
Teladoc Health Inc Added +179,500 +$1.26M 2.7%
Edgewise Therapeutics Inc New +38,343 +$951K 0.6%

Showing the 10 largest of 23 changes.

Q3 2025

quarter ended September 30, 2025 · filed November 19, 2025

Company Action Shares changed Value of change % of portfolio
Genedx Holdings Corp Exited −100,000 −$9.23M —
Springworks Therapeutics Inc Exited −150,000 −$7.05M —
Novavax Inc New +635,000 +$5.51M 3.4%
CD Centene Corp Del New +110,300 +$3.94M 2.5%
Genedx Holdings Corp Trimmed −32,500 −$3.5M 59.9%
Ardelyx Inc Trimmed −547,000 −$3.01M 2.2%
Teladoc Health Inc Added +324,416 +$2.51M 3.4%
Teladoc Health Inc Trimmed −279,600 −$2.16M 2.3%
Novavax Inc New +243,000 +$2.11M 1.3%
Personalis Inc New +229,435 +$1.5M 0.9%

Showing the 10 largest of 18 changes.

Q2 2025

quarter ended June 30, 2025 · filed August 15, 2025

Company Action Shares changed Value of change % of portfolio
Springworks Therapeutics Inc Exited −531,351 −$23.4M —
SS SPDR Ser Tr Exited −280,000 −$22.7M —
Genedx Holdings Corp New +100,000 +$9.23M 6.3%
Viking Therapeutics Inc Exited −336,700 −$8.13M —
Springworks Therapeutics Inc New +150,000 +$7.05M 4.8%
Teladoc Health Inc Added +605,800 +$5.28M 4.5%
Genedx Holdings Corp Trimmed −47,500 −$4.38M 58.4%
Ardelyx Inc Trimmed −973,710 −$3.82M 3.8%
Peloton Interactive Inc Exited −500,000 −$3.16M —
Teladoc Health Inc Trimmed −184,900 −$1.61M 2.3%

Showing the 10 largest of 14 changes.

Q1 2025

quarter ended March 31, 2025 · filed May 15, 2025

Company Action Shares changed Value of change % of portfolio
SS SPDR Ser Tr New +280,000 +$22.7M 11.5%
SS Select Sector SPDR Tr Exited −115,000 −$15.8M —
Springworks Therapeutics Inc Added +276,578 +$12.2M 11.8%
Viking Therapeutics Inc New +336,700 +$8.13M 4.1%
Genedx Holdings Corp Trimmed −53,514 −$4.74M 43.3%
Teladoc Health Inc New +565,900 +$4.5M 2.3%
Biohaven Ltd Trimmed −185,825 −$4.47M 8.1%
Biocryst Pharmaceuticals Inc Exited −535,558 −$4.03M —
Novavax Inc Exited −466,000 −$3.75M —
Peloton Interactive Inc New +500,000 +$3.16M 1.6%

Showing the 10 largest of 20 changes.

Q4 2024

quarter ended December 31, 2024 · filed February 14, 2025

Company Action Shares changed Value of change % of portfolio
SS Select Sector SPDR Tr New +115,000 +$15.8M 8.6%
SS SPDR Ser Tr Exited −100,000 −$9.88M —
Springworks Therapeutics Inc Added +220,573 +$7.97M 5.0%
Biohaven Ltd Added +146,520 +$5.47M 17.3%
Phathom Pharmaceuticals Inc Trimmed −604,423 −$4.91M 0.6%
Biohaven Ltd Trimmed −102,700 −$3.84M 4.1%
Myriad Genetics Inc Exited −134,500 −$3.68M —
Ardelyx Inc Added +720,231 +$3.65M 5.8%
Phathom Pharmaceuticals Inc Exited −192,700 −$3.48M —
EP Eyepoint Pharmaceuticals Inc Exited −350,000 −$2.8M —

Showing the 10 largest of 20 changes.

Q3 2024

quarter ended September 30, 2024 · filed November 14, 2024

Company Action Shares changed Value of change % of portfolio
SS SPDR Ser Tr New +100,000 +$9.88M 5.9%
Phathom Pharmaceuticals Inc Added +524,487 +$9.48M 8.1%
Biohaven Ltd Added +187,700 +$9.38M 9.1%
Novavax Inc New +534,600 +$6.75M 4.0%
Springworks Therapeutics Inc Trimmed −199,000 −$6.38M 0.7%
Phathom Pharmaceuticals Inc New +192,700 +$3.48M 2.1%
Genedx Holdings Corp Trimmed −60,000 −$2.55M 26.6%
Myriad Genetics Inc Added +74,500 +$2.04M 2.2%
Palantir Technologies Inc Trimmed −50,000 −$1.86M 0.4%
Myriad Genetics Inc Exited −74,500 −$1.82M —

Showing the 10 largest of 20 changes.

Q2 2024

quarter ended June 30, 2024 · filed August 14, 2024

Company Action Shares changed Value of change % of portfolio
Walgreens Boots Alliance Inc Exited −410,000 −$8.89M —
Springworks Therapeutics Inc Trimmed −188,383 −$7.1M 8.2%
Ardelyx Inc Trimmed −551,569 −$4.09M 10.3%
Biohaven Ltd Trimmed −104,400 −$3.62M 22.7%
EP Eyepoint Pharmaceuticals Inc Added +409,500 +$3.56M 3.6%
SS SPDR Ser Tr Exited −35,000 −$3.32M —
Phathom Pharmaceuticals Inc New +225,000 +$2.32M 2.2%
EP Eyepoint Pharmaceuticals Inc Trimmed −230,000 −$2M 1.9%
Myriad Genetics Inc New +74,500 +$1.82M 1.7%
Myriad Genetics Inc New +60,000 +$1.47M 1.4%

Showing the 10 largest of 28 changes.

Q1 2024

quarter ended March 31, 2024 · filed May 15, 2024

Company Action Shares changed Value of change % of portfolio
Teladoc Health Inc Exited −639,600 −$13.8M —
Springworks Therapeutics Inc Added +264,500 +$13M 13.8%
Quidelortho Corp Exited −172,100 −$12.7M —
Springworks Therapeutics Inc Trimmed −207,100 −$10.2M 1.4%
Genedx Holdings Corp Added +948,253 +$8.66M 6.8%
Ardelyx Inc Added +1,175,000 +$8.58M 9.9%
Ardelyx Inc Trimmed −1,154,100 −$8.42M 1.3%
Walgreens Boots Alliance Inc Added +310,000 +$6.72M 5.9%
PB Pacific Biosciences Calif In Trimmed −1,537,100 −$5.76M 0.6%
Biohaven Ltd Added +88,423 +$4.84M 29.2%

Showing the 10 largest of 29 changes.

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