Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.
Reported portfolio value by quarter (27 quarters reported)
$511M in Q2 2013 → $747M now. Hover for any quarter.
As reported for the quarter ended December 31, 2019. Activity is the change in share count since the prior quarter's filing.
| Holding | % of portfolio | Activity | Shares | Value |
|---|---|---|---|---|
| SS SPDR S&P 500 ETF Tr Put | 19.0% | Unchanged | 440,000 | $142M |
| IT Ishares Tr Put | 17.7% | New | 800,000 | $133M |
| SS SPDR Series Trust Put | 4.5% | Trimmed 50% | 350,000 | $33.3M |
| BP Biohaven Pharmactl Hldg Co L Call | 4.4% | Added 20% | 600,000 | $32.7M |
| BS Biodelivery Sciences Intl In | 3.6% | Unchanged | 4,300,066 | $27.2M |
| Viewray Inc | 3.1% | Added 86% | 5,574,366 | $23.5M |
| Amarin Corp PLC | 3.0% | Trimmed 33% | 1,049,244 | $22.5M |
| BP Biohaven Pharmactl Hldg Co L | 3.0% | Trimmed 23% | 409,338 | $22.3M |
| Alkermes PLC | 2.8% | Added 315% | 1,033,500 | $21.1M |
| Q Quotient Ltd | 2.5% | Added 225% | 1,994,183 | $19M |
| Eiger Biopharmaceuticals Inc | 2.5% | Trimmed 9.6% | 1,236,368 | $18.4M |
| Staar Surgical Co | 2.2% | New | 462,118 | $16.3M |
| IE Intersect Ent Inc | 2.1% | Trimmed 19% | 631,023 | $15.7M |
| PP Progenics Pharmaceuticals In | 2.1% | Added 93% | 3,060,923 | $15.6M |
| NT Nanostring Technologies Inc | 2.1% | Added 401% | 555,600 | $15.5M |
| Iovance Biotherapeutics Inc | 2.0% | Trimmed 53% | 533,301 | $14.8M |
| D Dermira Inc | 1.8% | Added 55% | 896,334 | $13.6M |
| RP Recro Pharma Inc | 1.8% | Trimmed 27% | 721,073 | $13.2M |
| LH Lantheus Hldgs Inc | 1.7% | New | 617,953 | $12.7M |
| Vapotherm Inc | 1.6% | New | 1,003,099 | $12.2M |
| S Sientra Inc | 1.5% | Trimmed 36% | 1,286,987 | $11.5M |
| Vericel Corp | 1.4% | Added 162% | 620,199 | $10.8M |
| LJ La Jolla Pharmaceutical Co | 1.4% | Added 1378% | 2,688,068 | $10.6M |
| AP Alexion Pharmaceuticals Inc | 1.2% | New | 83,100 | $8.99M |
| Sol Gel Technologies | 1.2% | Trimmed 7.4% | 521,819 | $8.95M |
| Relmada Therapeutics Inc | 1.2% | New | 220,724 | $8.61M |
| Aurinia Pharmaceuticals Inc | 1.1% | New | 400,000 | $8.1M |
| Avadel Pharmaceuticals PLC | 1.0% | Trimmed 67% | 1,029,012 | $7.77M |
| Exicure Inc | 1.0% | Added 17% | 2,707,851 | $7.74M |
| Z Zogenix Inc | 0.9% | Trimmed 2.2% | 134,937 | $7.03M |
| IM Icu Med Inc | 0.8% | Unchanged | 30,000 | $5.61M |
| LD Luminex Corp Del | 0.6% | New | 207,553 | $4.81M |
| Alkermes PLC Call | 0.5% | New | 200,000 | $4.08M |
| Strata Skin Sciences Inc | 0.5% | Trimmed 37% | 1,839,372 | $3.83M |
| Anaptysbio Inc | 0.5% | New | 221,600 | $3.6M |
| Aclaris Therapeutics Inc | 0.5% | Added 17% | 1,888,039 | $3.57M |
| MN Mylan N V | 0.4% | New | 150,000 | $3.02M |
| Heron Therapeutics Inc | 0.3% | Trimmed 8.7% | 89,730 | $2.11M |
| Scynexis Inc | 0.2% | New | 2,000,000 | $1.82M |
| Palatin Technologies Inc | 0.1% | Unchanged | 1,047,310 | $819K |
What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.
quarter ended December 31, 2019 · filed February 14, 2020
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| IT Ishares Tr | New | +800,000 | +$133M | 17.7% |
| SS SPDR Series Trust | Trimmed | −350,000 | −$33.3M | 4.5% |
| Iovance Biotherapeutics Inc | Trimmed | −597,800 | −$16.5M | 2.0% |
| Staar Surgical Co | New | +462,118 | +$16.3M | 2.2% |
| AP Allergan PLC | Exited | −96,504 | −$16.2M | — |
| Alkermes PLC | Added | +784,500 | +$16M | 2.8% |
| Avadel Pharmaceuticals PLC | Trimmed | −2,073,661 | −$15.7M | 1.0% |
| Mirati Therapeutics Inc | Exited | −200,000 | −$15.6M | — |
| Q Quotient Ltd | Added | +1,380,754 | +$13.1M | 2.5% |
| Nevro Corp | Exited | −150,510 | −$12.9M | — |
Showing the 10 largest of 52 changes.
quarter ended September 30, 2019 · filed November 14, 2019
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| SS SPDR S&P 500 ETF Tr | New | +440,000 | +$131M | 24.1% |
| SS SPDR Series Trust | New | +700,000 | +$53.4M | 9.9% |
| AT Aratana Therapeutics Inc | Exited | −7,258,135 | −$37.5M | — |
| Nevro Corp | Trimmed | −337,755 | −$29M | 2.4% |
| Amarin Corp PLC | Added | +1,278,011 | +$19.4M | 4.4% |
| IE Intersect Ent Inc | New | +779,134 | +$13.3M | 2.5% |
| Abbvie Inc | New | +154,500 | +$11.7M | 2.2% |
| Heron Therapeutics Inc | Trimmed | −559,761 | −$10.4M | 0.3% |
| WM Wright Med Group N V | Added | +492,100 | +$10.2M | 2.4% |
| R Retrophin Inc | Exited | −500,000 | −$10M | — |
Showing the 10 largest of 50 changes.
quarter ended June 30, 2019 · filed August 14, 2019
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Iovance Biotherapeutics Inc | Trimmed | −2,769,004 | −$67.9M | 8.3% |
| Mirati Therapeutics Inc | New | +200,000 | +$20.6M | 4.5% |
| AP Allergan PLC | New | +114,804 | +$19.2M | 4.2% |
| BP Biohaven Pharmactl Hldg Co L | Added | +429,979 | +$18.8M | 6.4% |
| BP Biohaven Pharmactl Hldg Co L | New | +400,000 | +$17.5M | 3.8% |
| Myriad Genetics Inc | Exited | −500,000 | −$16.6M | — |
| Eiger Biopharmaceuticals Inc | Added | +1,462,837 | +$15.5M | 3.8% |
| AP Adamas Pharmaceuticals Inc | Trimmed | −2,028,806 | −$12.6M | 0.6% |
| Aclaris Therapeutics Inc | Exited | −2,030,925 | −$12.2M | — |
| Catalyst Pharmaceuticals Inc | Trimmed | −3,091,928 | −$11.9M | 2.3% |
Showing the 10 largest of 49 changes.
quarter ended March 31, 2019 · filed May 15, 2019
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| SS SPDR S&P 500 ETF Tr | Exited | −700,000 | −$175M | — |
| SS SPDR Series Trust | Exited | −700,000 | −$50.2M | — |
| T Tesaro Inc | Exited | −442,219 | −$32.8M | — |
| T Tesaro Inc | Exited | −325,000 | −$24.1M | — |
| Myriad Genetics Inc | New | +500,000 | +$16.6M | 3.4% |
| Iovance Biotherapeutics Inc | Trimmed | −1,622,850 | −$15.4M | 8.5% |
| GB Global Blood Therapeutics In | Exited | −350,000 | −$14.4M | — |
| Dexcom Inc | Trimmed | −112,400 | −$13.4M | 1.7% |
| Nevro Corp | Exited | −300,000 | −$11.7M | — |
| AT Aratana Therapeutics Inc | Added | +3,175,000 | +$11.4M | 5.4% |
Showing the 10 largest of 50 changes.
quarter ended December 31, 2018 · filed February 14, 2019
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| SS SPDR S&P 500 ETF Tr | New | +700,000 | +$175M | 23.0% |
| IT Ishares Tr | Exited | −400,000 | −$67.4M | — |
| SS SPDR Series Trust | Added | +540,000 | +$38.7M | 6.6% |
| Nevro Corp | New | +744,415 | +$29M | 3.8% |
| T Tesaro Inc | Added | +337,519 | +$25.1M | 4.3% |
| Amarin Corp PLC | Exited | −1,455,000 | −$23.7M | — |
| CI Corium Intl Inc | Exited | −2,368,557 | −$22.5M | — |
| Dexcom Inc | Added | +155,700 | +$18.7M | 2.8% |
| Tandem Diabetes Care Inc | Trimmed | −483,979 | −$18.4M | 0.4% |
| T Tesaro Inc | Added | +200,000 | +$14.8M | 3.2% |
Showing the 10 largest of 57 changes.
quarter ended September 30, 2018 · filed November 14, 2018
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| IT Ishares Tr | New | +400,000 | +$67.4M | 9.9% |
| Mirati Therapeutics Inc | Trimmed | −662,506 | −$31.2M | 2.5% |
| EI Endo Intl PLC | Exited | −2,591,573 | −$24.4M | — |
| HP Horizon Pharma PLC | Trimmed | −929,043 | −$18.2M | 1.2% |
| Exact Sciences Corp | Exited | −261,400 | −$15.6M | — |
| SS SPDR Series Trust | New | +160,000 | +$15.3M | 2.3% |
| NT Nanostring Technologies Inc | New | +850,000 | +$15.2M | 2.2% |
| Z Zogenix Inc | Exited | −335,000 | −$14.8M | — |
| Xenon Pharmaceuticals Inc | New | +895,553 | +$11.8M | 1.7% |
| CI Corium Intl Inc | Trimmed | −1,228,500 | −$11.7M | 3.3% |
Showing the 10 largest of 53 changes.
quarter ended June 30, 2018 · filed August 14, 2018
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Iovance Biotherapeutics Inc | Added | +3,233,618 | +$41.4M | 8.4% |
| Heron Therapeutics Inc | Trimmed | −1,061,629 | −$41.2M | 3.2% |
| EI Endo Intl PLC | New | +2,591,573 | +$24.4M | 3.8% |
| Mirati Therapeutics Inc | Trimmed | −423,770 | −$20.9M | 7.9% |
| HP Horizon Pharma PLC | Trimmed | −1,224,600 | −$20.3M | 3.5% |
| GP Gw Pharmaceuticals PLC | Exited | −175,030 | −$19.7M | — |
| Angiodynamics Inc | Exited | −911,707 | −$15.7M | — |
| Exact Sciences Corp | New | +261,400 | +$15.6M | 2.5% |
| Z Zogenix Inc | New | +335,000 | +$14.8M | 2.3% |
| N Nuvasive Inc | Exited | −258,292 | −$13.5M | — |
Showing the 10 largest of 64 changes.
quarter ended March 31, 2018 · filed May 14, 2018
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Mirati Therapeutics Inc | Trimmed | −1,003,798 | −$30.8M | 6.9% |
| I Ignyta Inc | Exited | −1,150,119 | −$30.7M | — |
| AP Adamas Pharmaceuticals Inc | New | +1,135,203 | +$27.1M | 4.2% |
| Iovance Biotherapeutics Inc | Trimmed | −1,427,624 | −$24.1M | 2.4% |
| EI Endo Intl PLC | Exited | −2,442,323 | −$18.9M | — |
| LJ La Jolla Pharmaceutical Co | Added | +626,854 | +$18.7M | 7.7% |
| Angiodynamics Inc | Trimmed | −820,654 | −$14.2M | 2.5% |
| Heron Therapeutics Inc | Trimmed | −447,102 | −$12.3M | 6.8% |
| AP Amag Pharmaceuticals Inc | New | +598,800 | +$12.1M | 1.9% |
| KP Kala Pharmaceuticals Inc | New | +681,239 | +$10.8M | 1.7% |
Showing the 10 largest of 56 changes.
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