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Super Investors Crestline Management, L.P.
CM

Crestline Management, L.P.

Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.

Portfolio value
$53.5M
Positions
3
Quarter ended
June 30, 2026
Filed
August 14, 2026

Reported portfolio value by quarter (47 quarters reported)

$3.01B $46.3M
Q4 14 Q2 17 Q4 19 Q2 22 Q4 24 Q2 26

$1.41B in Q4 2014 → $53.5M now. Hover for any quarter.

Holdings

As reported for the quarter ended June 30, 2026. Activity is the change in share count since the prior quarter's filing.

Holding % of portfolio Activity Shares Value
Denali Therapeutics Inc 91.9% Trimmed 14% 1,910,732 $49.1M
Sana Biotechnology Inc 4.9% Unchanged 755,736 $2.64M
8N 8x8 Inc New 3.2% Unchanged 990,850 $1.69M

Timeline of changes

What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.

Q2 2026

quarter ended June 30, 2026 · filed August 14, 2026

Company Action Shares changed Value of change % of portfolio
Denali Therapeutics Inc Trimmed −300,000 −$7.72M 91.9%

Q1 2026

quarter ended March 31, 2026 · filed May 15, 2026

Company Action Shares changed Value of change % of portfolio
Denali Therapeutics Inc Trimmed −600,000 −$11.5M 91.7%
Sana Biotechnology Inc Trimmed −465,201 −$1.34M 4.7%
8N 8x8 Inc New Added +270 +$448 3.6%

Q4 2025

quarter ended December 31, 2025 · filed February 17, 2026

Company Action Shares changed Value of change % of portfolio
Denali Therapeutics Inc Trimmed −600,000 −$9.91M 87.0%
Sana Biotechnology Inc Trimmed −600,000 −$2.44M 9.3%

Q3 2025

quarter ended September 30, 2025 · filed November 14, 2025

Company Action Shares changed Value of change % of portfolio
Denali Therapeutics Inc Trimmed −450,000 −$6.53M 85.3%
Sana Biotechnology Inc Trimmed −600,000 −$2.13M 11.1%

Q2 2025

quarter ended June 30, 2025 · filed August 14, 2025

Company Action Shares changed Value of change % of portfolio
Denali Therapeutics Inc Trimmed −300,000 −$4.2M 86.3%
Sana Biotechnology Inc Trimmed −370,000 −$1.01M 10.6%

Q1 2025

quarter ended March 31, 2025 · filed May 15, 2025

Company Action Shares changed Value of change % of portfolio
IT Ishares Tr Exited −640,000 −$377M —
Nvidia Corporation Exited −703,108 −$94.4M —
IQ Invesco Qqq Tr Exited −150,000 −$76.7M —
SS SPDR S&P 500 ETF Tr Exited −125,000 −$73.3M —
SS SPDR S&P 500 ETF Tr Exited −104,000 −$61M —
Amazon Com Inc Exited −247,251 −$54.2M —
Alphabet Inc Exited −233,078 −$44.1M —
Johnson & Johnson Exited −238,615 −$34.5M —
CS Cisco Sys Inc Exited −519,377 −$30.7M —
Microsoft Corp Exited −70,464 −$29.7M —

Showing the 10 largest of 705 changes.

Q4 2024

quarter ended December 31, 2024 · filed February 14, 2025

Company Action Shares changed Value of change % of portfolio
IT Ishares Tr New +640,000 +$377M 12.5%
SS SPDR S&P 500 ETF Tr Exited −245,000 −$141M —
SS SPDR S&P 500 ETF Tr Trimmed −155,500 −$91.1M 2.0%
IQ Invesco Qqq Tr Added +148,475 +$75.9M 2.5%
SS SPDR S&P 500 ETF Tr New +125,000 +$73.3M 2.4%
Nvidia Corporation Added +431,805 +$58M 3.1%
Amazon Com Inc Added +209,763 +$46M 1.8%
Alphabet Inc Added +228,978 +$43.3M 1.5%
Johnson & Johnson Added +227,837 +$32.9M 1.1%
CS Cisco Sys Inc Added +510,047 +$30.2M 1.0%

Showing the 10 largest of 886 changes.

Q3 2024

quarter ended September 30, 2024 · filed November 13, 2024

Company Action Shares changed Value of change % of portfolio
IT Ishares Tr Exited −335,000 −$183M —
SS SPDR S&P 500 ETF Tr New +259,500 +$149M 7.7%
SS SPDR S&P 500 ETF Tr New +245,000 +$141M 7.3%
IT Ishares Tr Exited −133,000 −$27M —
Salesforce Inc Added +87,140 +$23.9M 1.3%
Apple Inc Trimmed −97,000 −$22.6M 0.2%
LW Lamb Weston Hldgs Inc Exited −251,414 −$21.1M —
Broadcom Inc Added +105,435 +$18.2M 1.0%
Coherent Corp New +202,889 +$18M 0.9%
AP Algonquin Pwr Utils Corp Exited −2,705,682 −$15.9M —

Showing the 10 largest of 555 changes.

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