Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.
Reported portfolio value by quarter (39 quarters reported)
$1.65B in Q2 2013 → $109M now. Hover for any quarter.
As reported for the quarter ended December 31, 2022. Activity is the change in share count since the prior quarter's filing.
| Holding | % of portfolio | Activity | Shares | Value |
|---|---|---|---|---|
| Biomarin Pharmaceutical Inc | 34.9% | Trimmed 52% | 367,765 | $38.1M |
| Dexcom Inc | 33.4% | Added 27% | 321,380 | $36.4M |
| Cytokinetics Inc | 6.9% | Trimmed 62% | 164,440 | $7.53M |
| Acrivon Therapeutics Inc | 3.0% | New | 284,201 | $3.27M |
| Hyperfine Inc | 3.0% | Added 41% | 3,880,900 | $3.26M |
| Alkermes PLC | 2.6% | Trimmed 64% | 110,000 | $2.87M |
| Conmed Corp | 2.2% | New | 27,500 | $2.44M |
| Neurocrine Biosciences Inc | 2.2% | Trimmed 7.9% | 20,000 | $2.39M |
| Syndax Pharmaceuticals Inc | 1.6% | Trimmed 92% | 70,000 | $1.78M |
| CT Chinook Therapeutics Inc | 1.4% | Trimmed 78% | 60,000 | $1.57M |
| Intuitive Surgical Inc | 1.4% | New | 5,750 | $1.53M |
| Blueprint Medicines Corp | 1.2% | Trimmed 71% | 30,000 | $1.31M |
| Geron Corp | 1.1% | Trimmed 74% | 500,000 | $1.21M |
| Penumbra Inc | 1.0% | New | 5,000 | $1.11M |
| Rocket Pharmaceuticals Inc | 0.9% | Trimmed 89% | 50,000 | $979K |
| Rain Oncology Inc | 0.9% | New | 120,000 | $960K |
| IM Inspire Med Sys Inc | 0.8% | Trimmed 91% | 3,500 | $882K |
| SR Silk Rd Med Inc | 0.7% | New | 15,000 | $793K |
| Immunogen Inc | 0.7% | Trimmed 88% | 150,000 | $744K |
| Eqrx Inc | 0.0% | Unchanged | 35,239 | $9.45K |
| EB Eucrates Biomedical Acqu Cor | 0.0% | Unchanged | 78,059 | $4.34K |
| MS Medicus Sciences Acquisition | 0.0% | Unchanged | 29,776 | $2.68K |
What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.
quarter ended December 31, 2022 · filed February 15, 2023
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Abbvie Inc | Exited | −310,250 | −$41.6M | — |
| Agilent Technologies Inc | Exited | −338,030 | −$41.1M | — |
| Biomarin Pharmaceutical Inc | Trimmed | −391,273 | −$40.5M | 34.9% |
| Boston Scientific Corp | Exited | −958,600 | −$37.1M | — |
| LE Lilly Eli & Co | Exited | −103,150 | −$33.4M | — |
| A Amerisourcebergen Corp | Exited | −239,150 | −$32.4M | — |
| Unitedhealth Group Inc | Exited | −62,980 | −$31.8M | — |
| Danaher Corporation | Exited | −117,800 | −$30.4M | — |
| Tenet Healthcare Corp | Exited | −518,990 | −$26.8M | — |
| Thermo Fisher Scientific Inc | Exited | −51,240 | −$26M | — |
Showing the 10 largest of 62 changes.
quarter ended September 30, 2022 · filed November 14, 2022
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Biogen Inc | Trimmed | −343,690 | −$91.8M | 2.3% |
| HT Horizon Therapeutics Pub L | Trimmed | −674,320 | −$41.7M | 1.8% |
| Abbvie Inc | New | +310,250 | +$41.6M | 5.2% |
| RT Revance Therapeutics Inc | Trimmed | −1,353,498 | −$36.5M | 0.2% |
| Natera Inc | Trimmed | −833,290 | −$36.5M | 0.4% |
| Boston Scientific Corp | Trimmed | −849,390 | −$32.9M | 4.6% |
| C Chemocentryx Inc | Exited | −1,097,370 | −$27.2M | — |
| Thermo Fisher Scientific Inc | New | +51,240 | +$26M | 3.3% |
| Agilent Technologies Inc | Added | +199,750 | +$24.3M | 5.1% |
| CD Centene Corp Del | Trimmed | −239,890 | −$18.7M | 2.9% |
Showing the 10 largest of 68 changes.
quarter ended June 30, 2022 · filed August 15, 2022
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| SS SPDR Ser Tr | Exited | −600,000 | −$53.9M | — |
| Envista Holdings Corporation | Exited | −914,490 | −$44.5M | — |
| Abbvie Inc | Exited | −254,160 | −$41.2M | — |
| Teleflex Incorporated | Exited | −99,150 | −$35.2M | — |
| AL Abbott Labs | Trimmed | −285,440 | −$31M | 2.2% |
| Cvs Health Corp | Exited | −286,600 | −$29M | — |
| Humana Inc | Trimmed | −61,820 | −$28.9M | 2.2% |
| Hologic Inc | New | +402,110 | +$27.9M | 2.8% |
| Amgen Inc | Exited | −108,890 | −$26.3M | — |
| Cytokinetics Inc | Trimmed | −649,510 | −$25.5M | 1.9% |
Showing the 10 largest of 72 changes.
quarter ended March 31, 2022 · filed May 16, 2022
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Medtronic PLC | Exited | −1,530,580 | −$158M | — |
| Bristol-myers Squibb Co | Trimmed | −1,274,390 | −$93.1M | 2.6% |
| SS SPDR Ser Tr | New | +600,000 | +$53.9M | 3.6% |
| Jazz Pharmaceuticals PLC | Trimmed | −339,910 | −$52.9M | 0.1% |
| Johnson & Johnson | Exited | −279,810 | −$47.9M | — |
| Biomarin Pharmaceutical Inc | Added | +609,696 | +$47M | 4.0% |
| Tenet Healthcare Corp | Trimmed | −498,450 | −$42.8M | 1.6% |
| Cytokinetics Inc | Added | +1,040,990 | +$38.3M | 2.8% |
| BD Becton Dickinson & Co | New | +141,460 | +$37.6M | 2.5% |
| SS Select Sector SPDR Tr | Exited | −254,230 | −$35.8M | — |
Showing the 10 largest of 69 changes.
quarter ended December 31, 2021 · filed February 14, 2022
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Bristol-myers Squibb Co | Trimmed | −1,779,610 | −$111M | 6.1% |
| Medtronic PLC | Added | +918,100 | +$95M | 8.6% |
| Mckesson Corp | Trimmed | −378,400 | −$94.1M | 0.9% |
| Welltower Inc | Exited | −617,480 | −$50.9M | — |
| A Amerisourcebergen Corp | Trimmed | −375,760 | −$49.9M | 3.8% |
| Danaher Corporation | New | +150,590 | +$49.5M | 2.7% |
| Zimmer Biomet Holdings Inc | Exited | −330,590 | −$48.4M | — |
| HT Horizon Therapeutics Pub L | Trimmed | −445,958 | −$48.1M | 4.9% |
| A Anthem Inc | New | +101,560 | +$47.1M | 2.6% |
| Johnson & Johnson | Added | +272,530 | +$46.6M | 2.6% |
Showing the 10 largest of 93 changes.
quarter ended September 30, 2021 · filed November 15, 2021
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Bristol-myers Squibb Co | Added | +2,109,790 | +$125M | 9.2% |
| Regeneron Pharmaceuticals | Exited | −190,380 | −$106M | — |
| Humana Inc | Exited | −239,030 | −$106M | — |
| Danaher Corporation | Exited | −384,920 | −$103M | — |
| Cvs Health Corp | Trimmed | −1,093,530 | −$92.8M | 0.6% |
| Thermo Fisher Scientific Inc | Exited | −182,970 | −$92.3M | — |
| A Amerisourcebergen Corp | Added | +632,340 | +$75.5M | 4.6% |
| Encompass Health Corp | Trimmed | −935,716 | −$70.2M | 0.4% |
| Zimmer Biomet Holdings Inc | Trimmed | −433,740 | −$63.5M | 2.1% |
| CD Centene Corp Del | New | +982,630 | +$61.2M | 2.6% |
Showing the 10 largest of 77 changes.
quarter ended June 30, 2021 · filed August 16, 2021
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Vertex Pharmaceuticals Inc | Trimmed | −548,500 | −$111M | 1.0% |
| Regeneron Pharmaceuticals | New | +190,380 | +$106M | 4.3% |
| Cvs Health Corp | New | +1,267,330 | +$106M | 4.2% |
| Bristol-myers Squibb Co | New | +1,474,370 | +$98.5M | 3.9% |
| Incyte Corp | Exited | −1,144,287 | −$93M | — |
| Thermo Fisher Scientific Inc | New | +182,970 | +$92.3M | 3.7% |
| Natera Inc | New | +789,658 | +$89.7M | 3.6% |
| Biogen Inc | Added | +258,790 | +$89.6M | 4.7% |
| Agios Pharmaceuticals Inc | Exited | −1,532,960 | −$79.2M | — |
| Abbvie Inc | Exited | −729,420 | −$78.9M | — |
Showing the 10 largest of 110 changes.
quarter ended March 31, 2021 · filed May 17, 2021
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Danaher Corporation | New | +535,670 | +$121M | 4.3% |
| Madrigal Pharmaceuticals Inc | Exited | −902,601 | −$100M | — |
| Incyte Corp | Added | +1,124,757 | +$91.4M | 3.3% |
| CC Cooper Cos Inc | Trimmed | −232,463 | −$89.3M | 1.5% |
| Encompass Health Corp | New | +1,005,316 | +$82.3M | 2.9% |
| BR Bio Rad Labs Inc | Exited | −140,080 | −$81.7M | — |
| Bristol-myers Squibb Co | Exited | −1,297,700 | −$80.5M | — |
| Aurinia Pharmaceuticals Inc | Trimmed | −5,987,448 | −$77.7M | 0.4% |
| IH Iqvia Hldgs Inc | Trimmed | −401,620 | −$77.6M | 2.7% |
| Hologic Inc | Exited | −1,017,280 | −$74.1M | — |
Showing the 10 largest of 108 changes.
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