Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.
Reported portfolio value by quarter (51 quarters reported)
$359M in Q4 2013 → $767M now. Hover for any quarter.
As reported for the quarter ended June 30, 2026. Activity is the change in share count since the prior quarter's filing.
| Holding | % of portfolio | Activity | Shares | Value |
|---|---|---|---|---|
| TP Teva Pharmaceutical Inds Ltd | 6.6% | Added 32% | 1,500,082 | $50.8M |
| Mineralys Therapeutics Inc | 5.2% | Added 9.7% | 1,469,971 | $39.7M |
| Tower Semiconductor Ltd | 3.7% | Trimmed 26% | 108,265 | $28.2M |
| SS SPDR Series Trust Put | 3.1% | Trimmed 25% | 150,000 | $23.7M |
| Syndax Pharmaceuticals Inc | 2.9% | Added 40% | 1,014,606 | $22.2M |
| Biogen Inc Call | 2.8% | New | 100,000 | $21.6M |
| Biogen Inc | 2.7% | Added 4.4% | 96,626 | $20.9M |
| UP Ultragenyx Pharmaceutical In | 2.6% | Trimmed 27% | 588,494 | $19.6M |
| Biomarin Pharmaceutical Inc | 2.5% | Added 135% | 328,550 | $18.8M |
| Cytokinetics Inc | 2.4% | Added 452% | 219,987 | $18.7M |
| Bridgebio Pharma Inc | 2.4% | Added 0.0% | 245,346 | $18.3M |
| Cogent Biosciences Inc | 2.3% | Added 10% | 459,340 | $17.8M |
| Nova Ltd | 1.8% | Trimmed 53% | 25,169 | $13.7M |
| Insmed Inc | 1.7% | New | 118,800 | $12.7M |
| Maze Therapeutics Inc | 1.6% | Added 84% | 417,564 | $12.5M |
| Astrazeneca PLC | 1.5% | Unchanged | 62,530 | $11.9M |
| Sanofi Sa | 1.5% | Unchanged | 269,515 | $11.5M |
| Cybin Inc | 1.4% | Added 64% | 1,620,753 | $10.7M |
| EL Eli Lilly & Co | 1.3% | Trimmed 11% | 8,040 | $9.64M |
| Madrigal Pharmaceuticals Inc | 1.2% | Added 93% | 17,419 | $9.35M |
| Trevi Therapeutics Inc | 1.2% | Trimmed 13% | 499,029 | $9.31M |
| Acadia Pharmaceuticals Inc | 1.2% | Added 39% | 356,534 | $9.02M |
| CT Celldex Therapeutics Inc New | 1.2% | Trimmed 1.1% | 240,868 | $8.96M |
| Rhythm Pharmaceuticals Inc | 1.2% | New | 80,400 | $8.93M |
| Cytokinetics Inc Call | 1.1% | Trimmed 61% | 100,000 | $8.52M |
| Oric Pharmaceuticals Inc | 1.1% | Added 40% | 752,983 | $8.15M |
| Lam Research Corp | 1.0% | New | 18,470 | $8M |
| AM Applied Matls Inc | 1.0% | New | 11,040 | $7.98M |
| Tango Therapeutics Inc | 1.0% | Trimmed 26% | 254,250 | $7.95M |
| Novartis Ag | 1.0% | Added 35% | 50,000 | $7.83M |
| Solaredge Technologies Inc | 1.0% | Unchanged | 4,000,000 | $7.75M |
| Vor Biopharma Inc | 1.0% | Added 29% | 416,417 | $7.67M |
| Abbvie Inc | 1.0% | Unchanged | 30,256 | $7.61M |
| Merck & Co Inc | 1.0% | Added 21% | 58,600 | $7.53M |
| Johnson & Johnson | 1.0% | Unchanged | 28,831 | $7.32M |
| Ideaya Biosciences Inc | 1.0% | New | 196,408 | $7.32M |
| Immatics N.v | 1.0% | Added 3.4% | 720,057 | $7.29M |
| Nuvectis Pharma Inc | 0.9% | New | 382,945 | $7.04M |
| Pfizer Inc | 0.9% | Added 54% | 286,000 | $6.89M |
| HB Harmony Biosciences Hldgs In | 0.8% | New | 176,663 | $6.43M |
| Xenon Pharmaceuticals Inc | 0.8% | Trimmed 17% | 105,000 | $6.34M |
| Climb Bio Inc | 0.8% | Added 15% | 483,747 | $6.31M |
| Zenas Biopharma Inc | 0.8% | Added 7.7% | 230,834 | $5.86M |
| NA Novo-nordisk A S | 0.8% | Unchanged | 120,677 | $5.79M |
| Enliven Therapeutics Inc | 0.7% | Trimmed 26% | 112,765 | $5.72M |
| Prelude Therapeutics Inc | 0.7% | Added 83% | 1,019,832 | $5.44M |
| Gsk PLC | 0.7% | Trimmed 16% | 102,000 | $5.35M |
| Forte Biosciences Inc | 0.7% | Added 35% | 249,693 | $5.31M |
| Bioage Labs Inc | 0.7% | Added 147% | 213,671 | $5.24M |
| SR Scholar Rock Hldg Corp | 0.7% | Unchanged | 94,265 | $5.18M |
| Satellos Bioscience Inc | 0.7% | Added 33% | 652,590 | $5.07M |
| Palisade Bio Inc | 0.6% | Added 30% | 2,257,106 | $4.72M |
| Eledon Pharmaceuticals Inc | 0.6% | Trimmed 33% | 1,191,187 | $4.69M |
| Vistra Corp | 0.6% | New | 29,450 | $4.67M |
| Talen Energy Corp | 0.6% | New | 12,135 | $4.66M |
| Savara Inc | 0.6% | Added 2.3% | 756,164 | $4.66M |
| Disc Medicine Inc | 0.6% | Added 19% | 63,538 | $4.65M |
| GX Global X Fds | 0.6% | New | 195,900 | $4.45M |
| Dyne Therapeutics Inc | 0.6% | Added 24% | 199,594 | $4.43M |
| Relay Therapeutics Inc | 0.6% | Trimmed 43% | 233,836 | $4.38M |
Showing top 60 of 105 positions.
What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.
quarter ended June 30, 2026 · filed August 14, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Biogen Inc | New | +100,000 | +$21.6M | 2.8% |
| Curis Inc | Trimmed | −1,895,941 | −$19.8M | 0.1% |
| Cytokinetics Inc | Added | +180,170 | +$15.3M | 2.4% |
| Nova Ltd | Trimmed | −28,197 | −$15.3M | 1.8% |
| Cytokinetics Inc | Trimmed | −159,300 | −$13.6M | 1.1% |
| Insmed Inc | New | +118,800 | +$12.7M | 1.7% |
| TP Teva Pharmaceutical Inds Ltd | Added | +363,107 | +$12.3M | 6.6% |
| Biomarin Pharmaceutical Inc | Added | +188,650 | +$10.8M | 2.5% |
| Tower Semiconductor Ltd | Trimmed | −37,470 | −$9.77M | 3.7% |
| Rhythm Pharmaceuticals Inc | New | +80,400 | +$8.93M | 1.2% |
Showing the 10 largest of 108 changes.
quarter ended March 31, 2026 · filed May 15, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Mineralys Therapeutics Inc | Added | +890,968 | +$24.1M | 5.8% |
| Cytokinetics Inc | New | +259,300 | +$17.1M | 2.7% |
| SS SPDR Series Trust | Added | +130,000 | +$16.6M | 4.1% |
| Astrazeneca PLC | Exited | −135,060 | −$12.4M | — |
| Astrazeneca PLC | New | +62,530 | +$12.3M | 2.0% |
| PP Praxis Precision Medicines I | Exited | −40,000 | −$11.8M | — |
| UP Ultragenyx Pharmaceutical In | Added | +508,710 | +$10.7M | 2.7% |
| Bridgebio Pharma Inc | Added | +137,500 | +$10.2M | 2.9% |
| Cellebrite Di Ltd | New | +631,521 | +$8.7M | 1.4% |
| Palo Alto Networks Inc | New | +52,800 | +$8.46M | 1.3% |
Showing the 10 largest of 107 changes.
quarter ended December 31, 2025 · filed February 17, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Nice Ltd | Exited | −157,400 | −$22.8M | — |
| Tower Semiconductor Ltd | Trimmed | −189,289 | −$22.2M | 2.8% |
| Merus N V | Exited | −150,000 | −$14.1M | — |
| IQ Invesco Qqq Tr | Exited | −22,960 | −$13.8M | — |
| TP Teva Pharmaceutical Inds Ltd | Trimmed | −383,500 | −$12M | 6.8% |
| Cogent Biosciences Inc | Added | +279,974 | +$9.94M | 2.6% |
| Cidara Therapeutics Inc | Exited | −100,000 | −$9.58M | — |
| Structure Therapeutics Inc | Trimmed | −132,931 | −$9.25M | 0.6% |
| Biomarin Pharmaceutical Inc | New | +147,000 | +$8.74M | 1.7% |
| SS SPDR Series Trust | New | +70,000 | +$8.54M | 1.6% |
Showing the 10 largest of 125 changes.
quarter ended September 30, 2025 · filed November 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Nice Ltd | New | +157,400 | +$22.8M | 4.8% |
| Syndax Pharmaceuticals Inc | Trimmed | −1,183,848 | −$18.2M | 1.3% |
| SS SPDR Series Trust | Exited | −200,000 | −$16.6M | — |
| Merus N V | New | +150,000 | +$14.1M | 3.0% |
| IQ Invesco Qqq Tr | New | +22,960 | +$13.8M | 2.9% |
| Nova Ltd | Trimmed | −31,940 | −$10.2M | 3.0% |
| Mineralys Therapeutics Inc | Trimmed | −261,064 | −$9.9M | 1.8% |
| Cidara Therapeutics Inc | New | +100,000 | +$9.58M | 2.0% |
| Cytokinetics Inc | Trimmed | −165,201 | −$9.08M | 1.9% |
| Nvidia Corporation | Exited | −54,515 | −$8.61M | — |
Showing the 10 largest of 119 changes.
quarter ended June 30, 2025 · filed August 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| IT Ishares Tr | Trimmed | −208,100 | −$18.4M | 1.0% |
| SS SPDR Series Trust | New | +200,000 | +$16.6M | 3.9% |
| Bridgebio Pharma Inc | Trimmed | −279,500 | −$12.1M | 0.9% |
| Tower Semiconductor Ltd | Added | +203,173 | +$8.81M | 2.7% |
| Biogen Inc | Added | +60,000 | +$7.54M | 2.4% |
| Forte Biosciences Inc | New | +495,109 | +$6.4M | 1.5% |
| UP Ultragenyx Pharmaceutical In | Trimmed | −167,300 | −$6.08M | 0.9% |
| Cytokinetics Inc | Added | +181,757 | +$6.01M | 2.5% |
| Moonlake Immunotherapeutics | New | +125,000 | +$5.9M | 1.4% |
| Cidara Therapeutics Inc | Added | +120,873 | +$5.89M | 1.6% |
Showing the 10 largest of 127 changes.
quarter ended March 31, 2025 · filed May 15, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| IT Ishares Tr | New | +255,100 | +$23.2M | 5.3% |
| Bridgebio Pharma Inc | Trimmed | −538,671 | −$18.6M | 2.9% |
| Microsoft Corp | Trimmed | −17,735 | −$6.66M | 0.4% |
| Meta Platforms Inc | Trimmed | −11,039 | −$6.36M | 1.3% |
| CP Check Point Software Tech Lt | Trimmed | −27,301 | −$6.22M | 0.4% |
| Acadia Pharmaceuticals Inc | Exited | −288,539 | −$5.29M | — |
| Wix Com Ltd | Trimmed | −30,453 | −$4.98M | 0.3% |
| Amazon Com Inc | Trimmed | −26,000 | −$4.95M | 1.6% |
| Jfrog Ltd | Trimmed | −147,510 | −$4.72M | 0.3% |
| Alphabet Inc | Trimmed | −30,000 | −$4.69M | 0.5% |
Showing the 10 largest of 102 changes.
quarter ended December 31, 2024 · filed February 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Apple Inc | Exited | −60,847 | −$14.2M | — |
| TP Teva Pharmaceutical Inds Ltd | Trimmed | −561,035 | −$12.4M | 6.3% |
| Amazon Com Inc | Trimmed | −43,000 | −$9.43M | 2.5% |
| Alphabet Inc | New | +43,500 | +$8.28M | 1.5% |
| Sentinelone Inc | Exited | −276,554 | −$6.62M | — |
| Annexon Inc | New | +1,243,039 | +$6.38M | 1.2% |
| Nice Ltd | Trimmed | −35,861 | −$6.09M | 1.3% |
| Nice Ltd | Exited | −32,100 | −$5.57M | — |
| Ormat Technologies Inc | New | +79,000 | +$5.35M | 1.0% |
| Eledon Pharmaceuticals Inc | Added | +1,254,298 | +$5.17M | 1.9% |
Showing the 10 largest of 111 changes.
quarter ended September 30, 2024 · filed November 14, 2024
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| TP Teva Pharmaceutical Inds Ltd | Exited | −3,268,900 | −$53.1M | — |
| VE Vaneck ETF Trust | Exited | −149,800 | −$39.1M | — |
| TP Teva Pharmaceutical Inds Ltd | Added | +1,340,800 | +$24.2M | 6.1% |
| Kezar Life Sciences Inc | Trimmed | −1,846,508 | −$14.3M | 0.3% |
| IQ Invesco Qqq Tr | Exited | −22,900 | −$11M | — |
| Nova Ltd | New | +51,960 | +$10.8M | 1.7% |
| Salesforce Inc | Exited | −33,600 | −$8.64M | — |
| Cytokinetics Inc | Trimmed | −159,903 | −$8.44M | 1.9% |
| Viking Therapeutics Inc | New | +133,066 | +$8.42M | 1.3% |
| Cybin Inc | New | +933,225 | +$8.3M | 1.3% |
Showing the 10 largest of 120 changes.
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